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You are here:  Home » News & Research » Hair Loss News Center » Follicle Multiplication & Hair Transplants - A Comparison
Gho's Follicular Multiplication - An Explanation
The big question seems to `always be "What is Dr. Gho doing, exactly". The following article was written by Dr. Gho for HairlossTalk to help clear up some of the misconceptions of exactly what Follicular Multiplication is - both for consumers and those in the Hair Transplant Industry...The Scientific Background of Follicular Multiplication

Since 1996, we have carried out fundamental studies on cell cultures, plucked
hair and performed biopsies on material. Recently, the results of one of our
fundamental studies have been published in the British Journal of Dermatology
(http://www.blackwell-synergy.com). In this publication we have revealed that
two distinct parts in hair follicles contain stem cell pools, which can induce
hair growth. The first area was found nearby the bulge area, the second area
in the outer root sheath of the lower part of the hair follicle. These pools
could also have been found on plucked hair and in our cell cultures. (This has
been presented at the European Cytoskeleton Meeting).


001aa.jpg
Longitudinally
sectioned hair follicle stained for follicular stem cells in red. Higher
magnifications (x40) of areas found to be positive for follicular stem
cell markers are shown next to the respective areas of the hair follicle.
Two areas were found to be positive for follicular stem cell markers;
i.e. the upper third (A) and lower third (B) of the hair follicle.

This was a part of the fundamental basis for Follicular Multiplication as well
as for Hair Multiplication.


Follicular Multiplication is a project that was started approximately eight
years ago, prior to Hair Multiplication. At that time we didn’t yet have
a name for this project, called the Follicular Multiplication project today.
The main objective of this study was to determine the minimal quantity of (follicle)
tissue needed to regenerate completely normal hair growth. All these studies
resulted in the patented GHO method of Follicular Multiplication.


In the Follicular Multiplication study, we revealed four remarkable
discoveries:


1. The whole follicle is not needed to regenerate hair growth. The upper part
of the follicle can regenerate a completely differentiated hair. This was proven
by the partial follicular unit transplantation study. With this study we revealed
that it was not necessary to transplant the entire follicular unit to regenerate
differentiated hair growth, but only a part of the follicular unit.


gho02.jpg gho01.jpg gho03.jpg
Partial Follicle Units Partial Follicle Units after Implantation Re-growth after Implantation


(Continued on the next page...)

- For more information on hair transplants, visit our Hair Transplants section.
- Discuss Hair Transplant Surgeons with others in our Hair Transplant Forums
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