In this study, we examined the mechanism of hair regression induced by endothelins in in vivo and in vitro study. Histological examination revealed that the catagen-like morphological change of anagen…
In this investigation we have designed to find out whether Dermal Papilla cells secrete growth factors like IGF-1, and the effect of androgens on their expression of the above growth…
Estrogens may play a protective role against the development of Androgenetic Alopecia, because pregnant women are in some way protected form androgenetic hair loss…
The objective of the study was to determine whether age affects the concentration of free amino acids in hair roots in men from the UK..
In order to investigate how the expression of epidermal proteins associated with differentiation also occurs in hair follicles according to its cycle, we performed immunohistochemistry and…
Neurotrophins have several non-neuronal functions in the skin. Previously we have shown that p75 kD neurotrophin receptor plays an important role during HF morphogenesis and that neurotrophins…
One of the most accepted means to identify keratinocyte stem cells takes advantage of the fact that they are normally rarely cycling in vivo, and can be detected experimentally as the…
Three double-blind, randomized, placebo-controlled studies were conducted in 1879 men ages 18 to 41 years with mild to moderate hair loss. Two of the studies enrolled men with…
Epithelial-mesenchymal interactions govern the initiation of organ development, subsequent morphogenesis and terminal cytodifferentiation. The developing tooth of the mouse is a good model for…
It is well known that sex hormones such as androgen and estrogen influence the hair growth in several animals. Aromatase is a member of cytochrome P-450 gene superfamily and…
