Recent content by ChemHead

because mice are cheaper and they are human skin xenografted so it doesn't really matter what animal they use.

Great news. Perhaps, the baldcel will become an extinct creature by 2030. In the meantime, we still have sterilization and trannymaxxing.

If a bear shits in the woods does anyone hear it drop? If a baldcel ropes, does anyone care? SchrödingersCatPilled

It's never reported. That's how little society cares about you if you're bald. Over.

Hmmmmmmmmm

Because it isn't normal. People have just deluded themselves into believing that it's normal because it happens to a bunch of other people and none of them actually understand what's going on. The shedding and dry hair was caused due to a lack of ability for the skin and hair to produce...

I think we all know that each of us often responds differently to the same drug and this comes down to genetic differences in enzyme expression, enzyme structure, and receptor expression and structure among a few other variables. It's my opinion that people who experience sheds on either finasteride or...

I actually don't believe that T influences hair loss at all. I think it's more of a neutral bystander. But if you can find a study that shows 5AR knockout mice lose hair via T, I might reconsider. My personal experience has proven to me that very high levels of T are completely harmless to...

It's just an AR agonist that lacks the ability to cause transcription of the same genes DHT does that contribute to hair loss.

I already explained it somewhere lost in this thread. Since Anavar isn't DHT, it won't have the same exact physiological effects as DHT... the genes transcribed when complexed with the androgen receptor will not be the same as DHT. However, since Anavar does still have anabolic and some...

The thread lives

It's difficult to know exactly what spironolactone is doing because of how many different pathways it affects. It's not just a mineralocorticoid receptor antagonist or a mild androgen receptor antagonist, there are like 10 different pathways spironolactone affects... 17α-hydroxylase...

I've used 5AR inhibitors on and off for the past decade. I've never felt worse in almost every regard (physically, psychologically and cognitively) than when I was using them. I was never more aggressive (and generally unpleasant as a human being) than when I was using a 5AR inhibitor. You're...

There are too many publications to name that demonstrate the importance of 5α-reduced steroids and DHT in mammalian physiology. Are they essential for existing? No, but I guess by that logic, eyes, fingers, a functioning dick, etc. are not essential for existence either. Just because some people...