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jondoeuk's latest activity
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
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Unlike oral finasteride or dutasteride, which reduce systemic DHT levels, pyrilutamide is designed to work locally with a different...
Yesterday at 1:45 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
It is critical to distinguish between a drug losing all efficacy and a drug peaking and stabilising. According to top-line data from...
Tuesday at 2:56 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
Yes. (2026-03-18) ''In terms of efficacy: compared to the placebo group, both 1.0% BID (i.e. twice a day) group and 0.5% BID group...
Tuesday at 2:51 PM
J
jondoeuk
replied to the thread
What are your thoughts on UCLA PP405? Do you think it is promising?
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New PP405 Phase 2/3 https://clinicaltrials.gov/study/NCT07819435 Estimated start date of Sept 2026. Primary completion date of Dec...
Tuesday at 1:08 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
You brought up ''drug resistance'' and all I said was that in individuals who have exceptionally high systemic or localised scalp DHT...
Monday at 3:41 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
The second phase III clinical trial was successful. Per Kintor, pyrilutamide has entered the new drug application stage in China. If...
Monday at 3:11 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
Yes. In preclinical binding assays, pyrilutamide demonstrates significantly higher potency than other prominent androgen receptor...
Sunday at 1:59 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
RU58841 has no published clinical safety or efficacy data in humans. Because both RU58841 and pyrilutamide are competitive blockers...
Sunday at 1:50 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
The half-life is approximately 6–8 hours.
Friday at 6:34 PM
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
The numbers show statistically significant and clinically meaningful hair growth outcomes, while demonstrating excellent safety. A total...
Friday at 6:13 PM
J
jondoeuk
replied to the thread
What are your thoughts on UCLA PP405? Do you think it is promising?
.
Triple Hair (Canada) began Phase 3 clinical trials for its Therapy-07 (THO7) topical in Vancouver, Canada, It contains minoxidil...
Sep 9, 2026
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
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See my reply to coco_304
Aug 31, 2026
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
Pyrilutamide (KX-826) is sold directly to consumers as a cosmetic under the brand name Koshine ahead of completing approval. You can buy...
Aug 31, 2026
J
jondoeuk
replied to the thread
Pyrilutamide (KX-826) 1.0% and 0.5%
.
Per Kintor's latest pipeline page modification, pyrilutamide has entered the new drug application stage in China. If the application is...
Aug 30, 2026
J
jondoeuk
replied to the thread
Kintor's GT20029 Topical for Androgenetic Alopecia
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Kintor plans to initiate the phase IIb/III clinical trial of GT20029 for male androgenetic alopecia in China this year.
Aug 30, 2026
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