Gadgetine

Recent content by randomuser1

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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    I believe this to be a very lazy and superficial video. I would need to repeat a lot of what I wrote in the long PDF I linked in the OP, but some of the key points that that guy misses: - lipid build-up on the skin: Why does he not question where it comes from? It is known that the skin...
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    My experimental finasteride/min h-responding method. Physio-metabolic treatment method for Androgenetic Alopecia.

    What hair loss meds was your uncle on before? In the case of your uncle and your friend, their results can be fully explained by hopping on treatment for the first time. Your gym friend's situation was not so bad so min/finasteride can do that alone. Your uncle at age 72 has very low T and DHT levels...
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    Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

    Amazing work my man. Regardless of whether your hypothesis holds true or not, the important thing is that you came up with something yourself and even collected data to back it up. Very valuable! I will have a more in-depth look at everything you wrote later but want to add three things: 1...
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    Disproving muscle-tension hair loss hypotheses

    Do you have sources for supporting this? Why would tension on its own lead to inflammation and calcification? Yes, inside a muscle tension can lead to inflammation, but the issue are the hairs. Also, calcification is not explained by this. On the other hand, there are literally dozens of...
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    Disproving muscle-tension hair loss hypotheses

    Because tension alone does not explain two other things happening: - fibrosis - calcification I'll extend what I said before: Inflammation + tension = fibrotic tissue regeneration Inflammation without tension = soft tissue regeneration (or if not soft at least much less fibrotic) No...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    Only partially genetic. Diet during childhood and adolescence plays a big role, maybe even the bigger one. (source 1, source 2) Definitely not genetic: Myopia - A modern yet reversible disease Partially genetic, partially not. (see for example here the examples of an Asian monk vs. a Native...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    But you know what causes excess sebum production? High-carb/high-sugar or lack of physical exercise. A list of just a few sources confirming this: Sebaceous gland lipids by M. Picardo et al: Source Source Source Source Source As you can see, insulin/carb/sugar issues are the main...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    It is a good question. The answer is: scalp tension. The perhaps most important thing to understand about scalp tension (and in fact any tension on the dermis) is that it is the strongest factor (among three or four) in determining whether the body will recreate tissue in a fibrotic or...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    Ah, not surprising! What I also found surprising was this post in the thread you linked: I haven't really dug into topical application of magnesium oil - maybe it could achieve what diet and supplements cannot? Inositol should totally help in slowing hair loss down. In fact there is a...
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    Baldness is high blood pressure and acute heart failure

    Sort of causal. The common root cause is insulin resistance. Insulin resistance leads to damages in the vasculature: both in the central vasculature (CVD) and in the peripheral capillaries in the scalp, leading to hair loss. Check out the PDF I attached to this post. It is a long read but...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    I think there are different mechanisms at play with estradiol: - Scavenging T and thus preventing conversion of T to DHT. Though this is likely not because of E2 itself but aromatase. Aromatase and 5ar compete for T. - Influencing subcutaneous fat storage. Fat cell injection seems to boost hair...
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    Disproving muscle-tension hair loss hypotheses

    @User27041995 I can help with this riddle. When the body recreates tissue (which was damaged or needs replacement for other reasons, e.g. due to chronic inflammatory processes) there are several factors which influence the decision whether new tissue is recreated fibrotic or non-fibrotic. The...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    Have you even had a look at the PDF I posted in the opening post? If what you say were true, then all genetically identical twins should be balding at the same speed. Have a look at pages 7 and 8. There I included photos from studies that compared the balding rates of monozygotic, so...
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    Original research theory: How Androgenetic Alopecia is a manifestation of insulin resistance and its connections with CVD & PCOS

    Long story short: Regrowth likely not possible. The only thing you can do is halt further hair loss progression. How would you do this? By eliminating all forms of insulin resistance, both primary (diet/exercise) and secondary (sleep, stress, avoiding overexercise, and a few others). Fermented...
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    Mane Biotech raises € 1.7 million to further develop its regenerative medicine technology to combat hair loss

    Their page on IndieGogo states February 2024 as the earliest shipping date. Guess it is on a first come first serve basis.
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