2 Months update on dutasteride-help

[Dani_uk]

Its coming upto the 2 month mark for me now. My original regiment of Propecia and 12.5% minoxidal with Alezic acid began to fade out at the 2-3 year mark.

I made the switch over from Propecia to dutasteride and also added topical spironolactone to my regimen.

I had some shedding even after the first week but having said that I noticed some small bumpy hairs growing out after 1 month when I ran my hand through the top. Now it seems as if nothing is happening. I cant really say it has improved or if the hairs just grew back from where they shed.

I feel so depressed

Any comments?

 

[JDW]

As long as it's not getting worse then call it a success. Myself and others have been on dutasteride for almost 10 months and have seen nothing but deterioration.
Are you sheddin gnow?

 

[OverMachoGrande]

Maintenance is success!!!! Regrowth is just an added benefit. If you stopped your hair loss you have overcome a huge obstacle. unk:

 

[JWM]

Or how about this...its only been TWO MONTHS!!!

Give it at LEAST a year before judging an oral 5ar inhibitor.

 

[Dani_uk]

Im still shedding, albeit slowly and then quickly its like it comes and goes....

Ive stopped the spironolactone cos it smells real bad and instead ive taken on alziec acid. I know when minoxidil reacts with spironolactone it stinks and I thik this was the case.

Im just peeved off... thats all!

I think its getting a bit thinner at the top actually, but what can I do?

 

[Dogs3]

hey propeciajunkie, where do you get your proscar at i was wondering? Do u buy generics online or get genuine through a prescription or get genuine online or what?

I was taking genuine through a prescription but it costs too much, now that i added genuine avodart...I just ordered some Dr. Reddy's finast (generic proscar) off of united pharmacies. Ive heard its legit from a few people, what do u think?

 

[OverMachoGrande]

Hey Dogs3. I use Proscar from UP and also get Finpecia from there as well. No complaints at all. I also get Avodart and generic Dutas from there as well.

 

[Dogs3]

cool, hey by the way, did you get a shed when you started in the first couple months on dutasteride? Im at one month and i think i might be getting a bit of one, its hard to tell though.

 

[OverMachoGrande]

Not so much on dutasteride but when I started finasteride I shed like alot. I was on finasteride for 1 year and then through dutasteride into the mix, it seemed to have a drying effect on my hair in the beginning though.

 

[Dani_uk]

Hey Propecia Junkie, did you get regrwoth?

When i first started Propecia and Minoxidil 3 years ago I had exceptional results ma I grew back a LOT but over that period of time it has began to go back down. Ive switched to avodart now and just experienced on and off shedding, more than what I was gettin with Propecia, but less than what I got with Propecia when I started it.

So Im just gona have to wait I guess and see what happens.

 

[Timi]

.

 

[dresden]

Timi you've said that in probably 400 of your 450 posts.

 

[Dani_uk]

Ok, but what else is there?

This really sucks! Medicine is meant to work ! Maybe there is more

Does food type have an effect.

One of my mates has hair loss probs, like me, but he notices when he has his propecia on an empty stomache and doesnt eat too much during the day he doesnt lose as much hair!!!

I mean is there a link with this?

As for dutasteride- I have to stick it out as Propecia was dying out for me!

 

[OverMachoGrande]

Hey Propecia Junkie, did you get regrwoth?

When i first started Propecia and Minoxidil 3 years ago I had exceptional results ma I grew back a LOT but over that period of time it has began to go back down. Ive switched to avodart now and just experienced on and off shedding, more than what I was gettin with Propecia, but less than what I got with Propecia when I started it.

So Im just gona have to wait I guess and see what happens.

YES!, for the first 2 years I had fantastic results, after that they started to fade so eventually I added dutasteride but I have not been on it long enough to evaluate yet. But I am not losing hair though.

 

[el_duterino]

Dani_uk, how much dutasteride are you taking ? for these antiandrogenes to work for ADVANCED/AGGRESSIVE Hairloss stage (meaning 1 dose of Propecia a day is not sufficient anymore), you should aim higher in terms of suppression of the effects of DHT.

Keep in mind that by lowering your DHT, your body and your hair follicules compensate and are becoming more DHT sensitive. That's why the the drop in libido experienced when starting dutasteride is usually improving after 1 to 2 years.
That's why some people reported negative results and further loss at the hairline, on dutasteride/finasteride alone. AR did become more DHT sensitive and offset the effects of the drug because there was enough DHT left over to bind to the AR.

Also, your hair are becoming more DHT sensitive over time, as many are genetically programmed to bald more with age. So what worked last year might not be enough now.

I take 0.5 mg a day. I also added Flutagel 1 application a day. My androgen-hungry receptors are binding very well with Flutamide and I don't to need take more dutasteride to lower my DHT to zero.
This will buy me some time (I am 41). See my pics under the flutagel hairline thread. It has been 2 months now and the results are excellent.

If I start loosing ground again, I will increase the number of applications of Flutagel over the day.
As soon as ASC-J9 is released, I will add this too...ASC-J9 is supposed to DESTROY AR.

The goal is to get close to a castrated men level, where no more DHT is around, therefore no more further hairloss is GUARANTEED. Anything less than that is a risk and we cannot blame the drugs to be not working.

 

[el_duterino]

About the link with food: yes I noticed the same when I was on finasteride. Empty stomach => more concentration of Finasteride in the blood for a few hours => more DHT reduction during that time => less hair loss.

finasteride has a shorter half-life than dutasteride.
With dutasteride the effects from food should have less impact, as the blood concentration stays steady during the day.
At least thats what I noticed when I made the switch.

Cheers
El Duterino

 

[Dogs3]

el dutasteride, did you have success with dutasteride before starting flutagel?..also, where do you buy the flutagel at, the only anti androgen im on is nizoral shampoo right now, im hoping that might help counter some of the effets of the rise in scalp T from the avodart....by the way, where do you buy your flutagel?


By the way, dani, two months is nothing man, youve got to give it at LEAST 6 or 7 to evaluate progress, but dont give it until a full year to evaluate results.

 

[Dani_uk]

Thanks a lont guys...

I used to take Propecia 1 mg tab a day with 12.5 minoxidil(+5% Alz acid)...(2.5-3 years)- with the effect wearing off

Now I am on dutasteride 0.5 + 12.5 minoxidil(5% Alz A) and 5%minoxidil(5% Alz acid).

Al Duterino- I am a little confused, thanks for the lengthy post though lots of Info there. What doyou mean by more sensitive? If there is less of it around does it mean the little that still remains is more vicous. I am also wondering why does it attack at the hairline??? And You also mentiond ACS19 whats that? Im sorry about all the questions.

Propecia JUnkie- What other medication are you taking apart from dutasteride. And whilst you were on Propecia were you experiencing hair loss? And now has it stopped with dutasteride. Have you still kept the other components of you regimen the same? Have you had any shedds???

 

[Dani_uk]

Why 6-7 months and not a year?

el dutasteride, did you have success with dutasteride before starting flutagel?..also, where do you buy the flutagel at, the only anti androgen im on is nizoral shampoo right now, im hoping that might help counter some of the effets of the rise in scalp T from the avodart....by the way, where do you buy your flutagel?


By the way, dani, two months is nothing man, youve got to give it at LEAST 6 or 7 to evaluate progress, but dont give it until a full year to evaluate results.

 

[el_duterino]

el dutasteride, did you have success with dutasteride before starting flutagel?..also, where do you buy the flutagel at, the only anti androgen im on is nizoral shampoo right now, im hoping that might help counter some of the effets of the rise in scalp T from the avodart....by the way, where do you buy your flutagel?


By the way, dani, two months is nothing man, youve got to give it at LEAST 6 or 7 to evaluate progress, but dont give it until a full year to evaluate results.

Dogs3, I had great success with dutasteride alone, for the first 3-4 years. But recently I was slowly loosing ground.
I buy Flutagel from SINERE web site. I don't think the rising T is a big issue, but oral dutasteride at 0.5 mg a day still leaves about 10% of serum DHT and 40-50% scalp DHT, so Flutagel is a perfect addition to dutasteride.
As for the sensitivity, the body adapts to less androgenes over time, therefore the same amount of DHT can potentially do more harm, or if we put it another way a smaller amount of DHT can do more harm than before starting dutasteride. Adding this parameter to the fact that DHT sensivity increases over the years, and you have a good chance that "dutasteride does not work" will be posted once more here.

And don't expect any new hair re-growth, anti-androgenes are for maintenance only.The abscence of DHT will not bring your hairline back. Only the healthy follicules will thicken.

Since Flutamide has a strong affinity for the AR, this should put the balance back into normal?and hopefully the follicules will be less androgenes sensitive over time.

I love this Flutagel ! in fact I am upping my applications to 2 times a day, starting today.
As for ASC-j9, pls search the forum this has been well discussed before. AndroScience is the lab that is working on that, they have a web site too.

Cheers
El Duterino