2011 Topical With Results From Pilot Study, Thoughts?

[Badbald]

Sorry if this has been discussed before, I thought with all the talk recently of new topicals its worth having a look at this in regards to a lower systematic absorption solution to existing meds.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262531/


Theres also this , again apologies if its been discussed before but I think it helps in showing the effectiveness of topical finasteride

https://www.ncbi.nlm.nih.gov/pubmed/25657911


I think if your looking at a solution right here and right now going with H&Ws liposomal topical finasteride, minoxidil, nizoral (leaving on the scalp not washing off) then adding in some of the newer mechanisms we are seeing now with seti and ceti could help cover all basis's may be your very best bet.

I have recently started leaving nizoral shampoo (not cream) on scalp and notice straight away the burning feeling in my diffuse thinning area going, obviously it is an anti-inflammatory but who's to say that isn't having a direct effect on stopping the attack on the follicles, its been shown in studies that using the shampoo can help a minor amount in AA hairloss, now if it was left on for a much longer period of time say 8 hours instead of 2 or 3 minutes before showering it off, is it possible that the effects could be far greater? I guess its worth a shot until we have something else solid.

Also I think adding topical Valproic acid could really help with this protocol, it may also really help to wound but I would avoid wounding if using topical finasteride or dutasteride.

 

[Vinc2097]

Sorry if this has been discussed before, I thought with all the talk recently of new topicals its worth having a look at this in regards to a lower systematic absorption solution to existing meds.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262531/


Theres also this , again apologies if its been discussed before but I think it helps in showing the effectiveness of topical finasteride

https://www.ncbi.nlm.nih.gov/pubmed/25657911


I think if your looking at a solution right here and right now going with H&Ws liposomal topical finasteride, minoxidil, nizoral (leaving on the scalp not washing off) then adding in some of the newer mechanisms we are seeing now with seti and ceti could help cover all basis's may be your very best bet.

I have recently started leaving nizoral shampoo (not cream) on scalp and notice straight away the burning feeling in my diffuse thinning area going, obviously it is an anti-inflammatory but who's to say that isn't having a direct effect on stopping the attack on the follicles, its been shown in studies that using the shampoo can help a minor amount in AA hairloss, now if it was left on for a much longer period of time say 8 hours instead of 2 or 3 minutes before showering it off, is it possible that the effects could be far greater? I guess its worth a shot until we have something else solid.

Also I think adding topical Valproic acid could really help with this protocol, it may also really help to wound but I would avoid wounding if using topical finasteride or dutasteride.

leaving nizoral for 8 hours would be first disgusting if you go in public and second, for myself, leaving it for more than 10 minute would completly dry my scalp and forehead

 

[Badbald]

I get that but what im doing is leaving it on at night before bed so no one sees, if your worried about dryness then in the morning give it a wash

 

[joni106]

Leaving nizoral on the scalp for so long - not good.
Can do problems with the liver.
I put nizoral shampoo twice at week and not more than 5 min .

 

[Badbald]

Leaving nizoral on the scalp for so long - not good.
Can do problems with the liver.
I put nizoral shampoo twice at week and not more than 5 min .

really? what kinds of problems. Ive been applying and leaving it on, I notice all the burning sensation to go

 

[jamesbooker1975]

leaving nizoral for 8 hours would be first disgusting if you go in public and second, for myself, leaving it for more than 10 minute would completly dry my scalp and forehead

or simple get the cream !

 

[Vinc2097]

or simple get the cream !

what are actually the sides of leaving nizoral shampoo hours and hours on the scalp ?

 

[joni106]

really? what kinds of problems. Ive been applying and leaving it on, I notice all the burning sensation to go

It's okay to use two or three times a week and rinse after 5 minutes. More then there is more potential for systemic absorption. Ketoconazole is not a healthy liver.