5mg finasteride TWICE a day? What do you think?

[abovedagame]

Hi, so I recently got a haircut with my barber and he confirmed my thoughts...I am losing ground. I didnt even have to bring it up...he was cutting away and was like "heh....one side is receded back further than the other...."

Anyways, since generic proscar is available now considerably cheaper than finasteride, I was thinking about going straight to taking a 5mg dose twice a day (~12 hours apart). I came up with this idea after reviewing the graphs Bryan has on his site.

http://www.geocities.com/bryan50001/dutasteride2b.htm

My idea is to reduce that "sawtooth" variability of dht as much as I can.

Am I going to be wasting my time guys? Let me know what you think.

 

[Flavio]

10 mg everyday is A LOT of finasteride. Try 1 mg / day for a couple of months and if you're not happy with the results, then increase the dosage.

 

[BodyDysmorphic]

imo increasing the dosage is a waste of good finasteride

1-1.25 mg is sufficient

cheers mate

 

[abovedagame]

10 mg everyday is A LOT of finasteride. Try 1 mg / day for a couple of months and if you're not happy with the results, then increase the dosage.

Hey Flavio,

I've been on 1 mg finasteride for over 3 years, I think it's lost its ability to hold the tide .

 

[Boondock]

I think you're totally playing with fire on that kind of dosage. You're asking for sides at 10mg, and you'd have to be pretty resilient not to get them.

Also, I don't know how much difference high-dose finasteride actually makes. If you're willing to tolerate sides, and the current level of propecia isn't doing enough, you might want to give dutasteride a go.

Have you thought about mixing and matching a bit with treatments? Maybe throwing a different topical into the mix could do something for you, or maybe even giving the 'ol laser helmet a go could work.

 

[Bryan]

I think you're totally playing with fire on that kind of dosage. You're asking for sides at 10mg, and you'd have to be pretty resilient not to get them.

Odd, then, that early test subjects took as much as 80 mg/day of finasteride for a few months (that's EIGHT TIMES the larger dose the original poster is talking about) with no problems!

Why do some people think that it makes any difference at all which of these tiny finasteride doses you take?

 

[Boondock]

I don't know the precise in-and-outs of finasteride. All I know is that a lot of people get sides on 1mg, which leads me to believe that taking 80mg would be completely and utterly insane.

You might be fine, but equally you might end up with man boobs.

 

[Bryan]

I don't know the precise in-and-outs of finasteride. All I know is that a lot of people get sides on 1mg, which leads me to believe that taking 80mg would be completely and utterly insane.

Anybody who gets sides on 1 mg is going to get sides at virtually ANY dose which is above the threshold that actually significantly inhibits 5a-reductase. Since finasteride has a relatively "flat" dose-response, that's going to be any dose above about 0.05 mg/day for most people.

 

[icdalite]

Hmmm.. not sure about that.

Was on 1 mg finpecia for 9 months and no sides. Then went on to 1.25 mg of finscar, first 2 mnths nothing. Last 9 days my left side (chest area) there is a burning sensation the whole day.

Its only today that I woke up and don't feel this, hopefully my body has adjusted to the increase in dosage. Already started cutting 1/5 of fincar for next week. which means back to 1 mg in a way....

 

[Bryan]

Was on 1 mg finpecia for 9 months and no sides. Then went on to 1.25 mg of finscar, first 2 mnths nothing. Last 9 days my left side (chest area) there is a burning sensation the whole day.

Uh-huh. Yeah, I'm sure that extra ONE-QUARTER OF A MILLIGRAM was causing the burning sensation in your chest!! :smack:

Sheesh. Guys are unbelievably superstitious when it comes to something like this.

 

[abovedagame]

bryan, is there any benefit in moving to the 5 mg twice daily dose in your opinion?

 

[Bryan]

Sure. Obviously not a BIG benefit, but a very small one. I highly doubt that it would be worth the cost of the extra finasteride.

 

[icdalite]

Was on 1 mg finpecia for 9 months and no sides. Then went on to 1.25 mg of finscar, first 2 mnths nothing. Last 9 days my left side (chest area) there is a burning sensation the whole day.

Uh-huh. Yeah, I'm sure that extra ONE-QUARTER OF A MILLIGRAM was causing the burning sensation in your chest!! :smack:

Sheesh. Guys are unbelievably superstitious when it comes to something like this.

Did'nt expect that from the generally "knowledgeable" Bryan.

As I said in the earlier post have been on finasteride for almost a year now and even after upping the dose to 1.25 I did'nt experience sides for the first 2 mnths.

There's hundreds of posts on this forum where ppl have had to cut down dosage from 1 mg to 0.75 and 0.5 to avoid the sides.

tsk..tskk. you could've done better there Bryan.....

 

[abovedagame]

bumppppppppppppppp

 

[yourworld001]

This guy over at HLH took 50mg Finasteride and regrow his hair https://www.hairlosshelp.com/forums/messageview.cfm?catid=10&threadid=117558&highlight_key=y

 

[Michael1986]

This guy over at HLH took 50mg Finasteride and regrow his hair https://www.hairlosshelp.com/forums/messageview.cfm?catid=10&threadid=117558&highlight_key=y

Whoever he is, he must have a big wallet.

 

[Pixie]

From what I understand, finasteride has sharply diminishing returns when you up the dosage.

 

[Michael1986]

There's actually nothing to gain by taking finasteride at 50mg. All it will do is cost you a load of extra money. 50mg is hardly any more effective than 1mg or even 0.5mg. Finasteride has an essentially flat dose response curve for all doses of about 0.5mg and over. Even 0.2mg will inhibit close to the amount of DHT than 5mg (or 50mg) can inhibit.

 

[Retinoid]

There's actually nothing to gain by taking finasteride at 50mg. All it will do is cost you a load of extra money. 50mg is hardly any more effective than 1mg or even 0.5mg. Finasteride has an essentially flat dose response curve for all doses of about 0.5mg and over. Even 0.2mg will inhibit close to the amount of DHT than 5mg (or 50mg) can inhibit.

View attachment 98262

It seems to be dependent on the target tissues. Merck uses 5mg for BPH for a reason--1mg was not really that effective. For the scalp, high dosages of 5AR blockers do not seem to be required. But even so, 1mg is more effective than .25mg however not a lot more (.25mg grows about 75-80% as much hair as 1mg) and usually will cause much more side effects. Duasteride probably requires very low dosages to be effective for hair loss over long term, but there are no intensive studies on it.

 

[Michael1986]

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