9 days of cyclosporin and Follica

[michael barry]

Something just occured to me.


Heretofore, Ive warned that the human immune system might be the one things that stops Follica from being successful.

You see, miniaturized hairs from men with baldness have been moved to immuno-deficient (SCID) mice before, and they grew just as well as the hairs moved from the donor area did. The resulting conclusions were clear, the immune system is doing "something" to keep miniaturized hairs small, and thus wont allow them to re-enlarge despite anti-androgens like finasteride.

The topicals administered in the Follica patent are administered 3 days after the wounding until day 12 (days "3-12" in the patent). If a man simply used cyclosporin for this nine day period......................I'd imagine there would be nothing to keep the new hairs from forming "up there" at all.


For those who dont know, cyclosporin is the greatest trichotic we currently have, but if you kept taking it you wouldn't have an immune system after a while and you'd get deathly sick. I dont think 9 days of it would be fatal however...............



I just got a great deal more confident in the possibilities of this working---------surely at LEAST in the donor area.

 

[Matt27]

Interesting.

Michael, what is your opinion of Protopic (Tacrolimus) used as a topical for hairloss? A good friend of mine is a esthetician who can get me this (and just about anything else) pretty much for free. I was thinking of trying it, once every other day or so, for a few weeks to see how it does. I believe Dr. Lee tried it a few years ago and had 50/50 success with it. Half of his patients in his study responded very well to it while the other half didn't respond at all. I'm wondering if Protopic in conjunction with Flutagel would be a good combo.