A FYI link to a 1998 patent application for PGs

[waynakyo]

I am surprised that the role of PGs was known all the way back then, he emphasizes PGE2

https://patentimages.storage.googleapis.com/5a/f7/0e/4bde16c5d1d4a9/WO1998033497A1.pdf

But still we do not have a PG based therapy to this day.