Anybody Use Ru58841 Mixed With Stemoxydine? (i Am Very Confused As To How To Mix Them)

Zeta ascended

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I'm Norwood 2 at the moment. I have a lot of vellus hairs where my hairline was originally. I've been using minoxidil for a year now and I started using ru58841 2 months ago. I mix my ru with minoxidil but it seems like a very bad vehicle for it and it doesn't absorb well into my skin. I'm gonna try mixing the raw powder into this serioxyl which can be found on Amazon. Any body have experiences with it? How much ru should be mixed in? I'm really confused about how to make a 5% solution with stemoxydine?
 

Ollie

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a 5% solution means 50mg per ml of vehicle.

I wouldn't really bother with RU - literally no one apart from the 50 year old users here (who barely have hair loss) experience 'maintenance' with it.
 

Zeta ascended

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a 5% solution means 50mg per ml of vehicle.

I wouldn't really bother with RU - literally no one apart from the 50 year old users here (who barely have hair loss) experience 'maintenance' with it.
I only want to block dht topically since I still want to have stable dht levels. What is you're opinion on topical finasteride? I have read multiple studies showing that it reduced scalp dht with a minor affect on the body.
 

Ollie

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I only want to block dht topically since I still want to have stable dht levels. What is you're opinion on topical finasteride? I have read multiple studies showing that it reduced scalp dht with a minor affect on the body.

Yeah Fins dosage response curve is too flat to be used as a topical and not go systemic.

A few of us are about to start topical Hydroxyflutamide (Active metabolite of Flutamide) and will be reporting the benefits in the coming months.

If you really want a topical AA now however, and you have the money, then go for topical CB.
 

arnoldd

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Yeah Fins dosage response curve is too flat to be used as a topical and not go systemic.

A few of us are about to start topical Hydroxyflutamide (Active metabolite of Flutamide) and will be reporting the benefits in the coming months.

If you really want a topical AA now however, and you have the money, then go for topical CB.

Do you know if is it possible to make my own topical flutamide from the oral pill ? Im interesting as well to try this drug but i can get access only to the pill form.
 

Ollie

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Do you know if is it possible to make my own topical flutamide from the oral pill ? Im interesting as well to try this drug but i can get access only to the pill form.

Topical flutamide won’t work. Flutamide has to be metabolised by the liver to become it’s active (and 25x more potent) metabolite hydroxyflufamide.

Hemingway did a post a while back that led to the current group buy :

https://www.hairlosstalk.com/intera...abolite-of-flutamide-a-better-ru58841.121993/
 

arnoldd

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Topical flutamide won’t work. Flutamide has to be metabolised by the liver to become it’s active (and 25x more potent) metabolite hydroxyflufamide.

Hemingway did a post a while back that led to the current group buy :

https://www.hairlosstalk.com/intera...abolite-of-flutamide-a-better-ru58841.121993/

From this post i read that in topically form is slightly better than finasteride. I cant take finasteride because im allergic maybe can i try with this drug ? I know topically works a lot less than orally but better than nothing..
However there isnt any data about topical dosage.
 

Ollie

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From this post i read that in topically form is slightly better than finasteride. I cant take finasteride because im allergic maybe can i try with this drug ? I know topically works a lot less than orally but better than nothing..
However there isnt any data about topical dosage.

The only reason it worked in those studies was because it was in rodents - so what was happening was the flutamide was going systemic and the grafted human follicles were then benefiting from the systemic benefits of the metabolised oh-flut .
In humans topical flut won’t work - literally impossible. Not to mention you’ll be straining your liver long term from systemic absorption.

You’re welcome to join the next group buy for oh-flut but won’t be for another couple of months as we’ve just received our first batch. On the plus side based on what we know of it and it’s effect on gene expression, it should be far far more efficacious than finasteride.
 

arnoldd

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The only reason it worked in those studies was because it was in rodents - so what was happening was the flutamide was going systemic and the grafted human follicles were then benefiting from the systemic benefits of the metabolised oh-flut .
In humans topical flut won’t work - literally impossible. Not to mention you’ll be straining your liver long term from systemic absorption.

You’re welcome to join the next group buy for oh-flut but won’t be for another couple of months as we’ve just received our first batch. On the plus side based on what we know of it and it’s effect on gene expression, it should be far far more efficacious than finasteride.

yep i read its fuckin hard on the liver. i ordered some RU but i don't know if i have any chance that it can pass throw the customs of my country. im almost fucked.
 

Ollie

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yep i read its fuckin hard on the liver. i ordered some RU but i don't know if i have any chance that it can pass throw the customs of my country. im almost fucked.

Peoples orders go through to the US annd Canada fine so i would imagine Argentina should be too assuming its labeled correctly.
 

arnoldd

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Peoples orders go through to the US annd Canada fine so i would imagine Argentina should be too assuming its labeled correctly.

i contacted anageninc and they told me from their experiences the chances are 50%. i bought the solution, not the powder which should be more suspicious.
 

Ljames

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I'm looking at getting some pre mixed RU, I'm based in the UK and have found a site that is legit but am just wondering about the vehicle. If anyone could share an opinion it would be much appreciated

"M.Wt: 369.34
Formula: C17H18F3N3O3
4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Solubility: Polyglycols, Aqua, Ethanol
Purity: >99%"
 
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