Another method for measuring biological age is to look at how complex carbohydrates called glycans are attached to molecules in the body, a process called glycosylation.
Gordan Lauc and colleagues at the University of Zagreb in Croatia recently discovered that glycosylation of an antibody called immunoglobulin G changes as we get older, and that this can be used to
predict chronological age. When Lauc’s team compared 5117 people’s “glycan age” with known markers for health deterioration, such as insulin, glucose, BMI and cholesterol, they found that those who scored poorly on these markers also had an older glycan age.
“Your glycan age seems to reflect how much inflammation is occurring in the body,” says Lauc. Prolonged inflammation can make cells deteriorate faster, so having an accelerated glycan age could be used as an early warning signal that your health is at risk, he says.