They are not always apoptosis goal oriented as we think. As an example: caspase 1 will shred up the glucocorticoid receptor NOT leading to apoptosis but instead it can cause cancer.
There are a bunch of tidbits to grab out of this paper and for some of the PGE2 "niche" people it may provide them with some new information.
But one thing I found interesting was:
"Lysophosphatidylcholine (LPC) is another molecule which mediates caspase-activity-induced regenerative responses. It is produced by apoptotic cells, and its presence in the interstitial medium acts as an attraction signal to phagocytes (Lauber et al., 2003). Moreover, LPC induces the differentiation of keratinocytes, which is a necessary step in the wound healing response in skin (Ryborg et al., 2004)."
Remember the folklore about eggs being beneficial to hair growth?
https://www.sciencedirect.com/science/article/pii/S0022202X15303936
Minoxidil, L-α-phosphatidyl-L-serine dipalmitoyl, L-α-phosphatidic acid (sodium salt, prepared from egg yolk lecithin), L-α-lysophosphatidylcholine (prepared from egg yolk lecithin),
There are a bunch of tidbits to grab out of this paper and for some of the PGE2 "niche" people it may provide them with some new information.
But one thing I found interesting was:
"Lysophosphatidylcholine (LPC) is another molecule which mediates caspase-activity-induced regenerative responses. It is produced by apoptotic cells, and its presence in the interstitial medium acts as an attraction signal to phagocytes (Lauber et al., 2003). Moreover, LPC induces the differentiation of keratinocytes, which is a necessary step in the wound healing response in skin (Ryborg et al., 2004)."
Remember the folklore about eggs being beneficial to hair growth?
https://www.sciencedirect.com/science/article/pii/S0022202X15303936
Minoxidil, L-α-phosphatidyl-L-serine dipalmitoyl, L-α-phosphatidic acid (sodium salt, prepared from egg yolk lecithin), L-α-lysophosphatidylcholine (prepared from egg yolk lecithin),