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According to a study on a castor oil-diet on the synthesis of pge2 in pregnant rats (http://www.ncbi.nlm.nih.gov/pubmed/11263183), the only areas where increased pge2 content was recorded were in the portal vein, and intestinal mucosa, and there were NO observed significant changes in the peripheral blood of the rats. What this means is that the increase in pge2 is only isolated to affecting the intestinal region as the portal vein is the vein located within the stomach region and intestinal mucosa is obviously the mucus within the intestine region. This is further iterated by the fact that the levels of pge2 in the peripheral blood id not change, which illustrates that it is a local change as peripheral blood is basically the blood that is responsible for transporting nutrients throughout the body (i.e to the scalp). Therefore, it would be logical to conclude that the scalp receives little to no increase in pge2 from ORAL consumption of castor oil.