Combining Propecia and Dutasteride

[stan]

Has anyone had more success taking both Dutasteride AND Propecia

together once each day?

Also, is it safe?

 

[Private Ryan]

just use dutasteride alone... dutasteride is so strong that most likely you are wasting your money by using finasteride with it...

 

[Renegade]

This is exactly what I am about to start doing. I'm currently loading w/ dutasteride every day (for 1 month). Then, I will be doing dutas M/W/F and finpecia on the remaining days. It's better than finasteride alone for the crown but not as risky as dutasteride ED for the hairline. I would still recommend spironolactone 5% once a day at night though. Good luck with whatever you decide.

 

[Guest]

Then, I will be doing dutas M/W/F and finpecia on the remaining days. It's better than finasteride alone for the crown but not as risky as dutasteride ED for the hairline.

No.

The 3x a week of dutasteride will get to more DHT than finasteride 5 mg EVERY DAY would, so the dutasteride leaving none for finasteride to take care of. Adding finasteride on the remaining days will do nothing extra for your hairline.

 

[Renegade]

Sorry, but I don't buy that. finasteride on the non-dutasteride days would have to be better than nothing. The dutasteride does not "overlap" it - they have a cumulative effect.

Although, I will say this...I've been gettin such good results already from using dutasteride every day with spironolactone twice that I'm tempted to stay on the dutasteride every day and just keep up with the spironolactone twice a day.

The only reason I was planning on that combo was so that I wouldn't have to use the spironolactone twice a day to counteract the increased test at the front (as I am prone to losing ground there). With the new foam though, it's much less of a hassle. Just want to make more room for the tricomin (feels awesome!).

 

[MPBWarrior]

i think Jayman is right. dutasteride 3 times a week should make finasteride's action on the other days close to nothing. dutasteride has a long half-life so it'll still be around on the days u don't take it. it'll probably be a waste of money to have finasteride on the off-days if you're on dutasteride mon-wed-fri.

 

[Guest]

Sorry, but I don't buy that. finasteride on the non-dutasteride days would have to be better than nothing. The dutasteride does not "overlap" it - they have a cumulative effect.

Yes you're right. There is a type II that finasteride takes care of, and a separate type II that the follicle eaves open for dutasteride.

Wrong.

They do not have a cumulative effect. dutasteride has a super long half-life, many many times longer than finasteride. It is still at almost full strength 3-4 days later, but even not at full strength it is still taking care of about 95% of type II dht, while the best that 5 MG of finasteride can do when taken EVERY DAY is 90%.

Your statement that "finasteride on the non-dutasteride days would have to be better than nothing" is disingenuous as well as a straw man. dutasteride is not nothing when taken every other day or every 3 days. It is indeed almost as strong as taking it every day, and still much stronger than 5 mg or even 10 mg of finasteride a day. So what makes you think that taking 1 mg of finasteride 4 days a week will do anything extra for your hair? It makes NO sense.

It's not like dutasteride and finasteride get into your system and dutasteride goes in the crown area while finasteride protects your front from the dutasteride? Give me a break man.

As for this statement:

The only reason I was planning on that combo was so that I wouldn't have to use the spironolactone twice a day to counteract the increased test at the front

Are you stating that finasteride would replace your spironolactone as an anti androgen for the front and protect against increased testosterone? finasteride supposedly increases scalp testosterone just like dutasteride supposedly does, just not as much.

Do whatever you want, don't listen to advice on here. Just waste your money on finasteride instead of spending it on something that will actually give you a benefit in conjunction with dutasteride. I tried.

You taking finasteride in conjunction with dutasteride amounts to basically kicking a dead man(the dht). Good job.

The only reason to ever take finasteride along with dutasteride is if you think that your dutasteride may be fake.

 

[Renegade]

Fine. So much for my stupid-*** theory then. Anyone want to buy the finpecia that I don't need now?

 

[person_123]

i know this is probably a silly question.

but why is avodart not an fda approved hair loss treatment?

i mean, if it's stronger than finasteride, why is it not prescribed for hair loss?

what is it actually supposed to be used for?

and if it's meant to be used for something drastic, like to chemically neuter people. why not just decrease the dosage and make it safe for hair loss. like proscar and propecia. one is for enlarged prostate, one is for hair loss.

 

[Follically Challenged]

person_123, that's a good question. beats me.

5mg dutasteride is an FDA approved treatment for bph (benign prostate hyperplasia...a.k.a an enlarged prostate)

 

[Nathaniel]

i know this is probably a silly question.

but why is avodart not an fda approved hair loss treatment?

i mean, if it's stronger than finasteride, why is it not prescribed for hair loss?

what is it actually supposed to be used for?

and if it's meant to be used for something drastic, like to chemically neuter people. why not just decrease the dosage and make it safe for hair loss. like proscar and propecia. one is for enlarged prostate, one is for hair loss.

Dutasteride never underwent phase III trials for hairloss in order to be approved. The manufactures studied the market and found out the profits would not be enough to compensate the high price of such trials in order to be approved by the FDA.

 

[person_123]

Oh so that's why.

From what I've read, here is what I understand.

finasteride inhibits production of one type of dht.
dutasteride inhibits the production of another type of dht.

Now if we were to combine the drugs, 0.5mg of finasteride, 0.5mg of dutasteride. Into one convenient pill. We'd have a much more potent drug to combat hairloss.

We'd also be paying a hell of a lot more.

 

[joseph49853]

Oh so that's why.

From what I've read, here is what I understand.

finasteride inhibits production of one type of dht.
dutasteride inhibits the production of another type of dht.

Now if we were to combine the drugs, 0.5mg of finasteride, 0.5mg of dutasteride. Into one convenient pill. We'd have a much more potent drug to combat hairloss.

We'd also be paying a hell of a lot more.

We already have a drug that inhibits both types, and it's called Dutasteride. I simply won't take it because of the considerably longer half-life. The drug can actually stay detectable in the system for as much as six months. For me, a drug this powerful for hairloss seems like overkill.

Anyway, I personally wouldn't recommend taking both together. Or at least, I wouldn't. Either you take one, or the other.

 

[Guest]

Oh so that's why.

From what I've read, here is what I understand.

finasteride inhibits production of one type of dht.
dutasteride inhibits the production of another type of dht.

Now if we were to combine the drugs, 0.5mg of finasteride, 0.5mg of dutasteride. Into one convenient pill. We'd have a much more potent drug to combat hairloss.

We'd also be paying a hell of a lot more.

Person_123,

that's wrong.

finasteride blocks 90% of type II DHT in the follicles, at the 5 mg per dose a day. It inhibits a very tiny amount of type I. At 1 mg a day I think it inhibits about 80-85% of type II DHT, although I could be wrong.

dutasteride blocks 98.5% of type II DHT in the follicles, at the 0.5 mg per dose per day. It inhibits 50% of type I as well.

So if you are taking dutasteride, taking finasteride along with it will provide no additional benefit. It would be near impossible to combine finasteride and dutasteride into one drug, but what would be the point? dutasteride does everything finasteride can do and more. It blocks 90%+ more DHT than finasteride does.