Consensus On Spironolactone - An Alternative To Other Antiandrogens

[sonictemples]

How is Spironolactone? Does it work topically, do people get sides on topical

 

[Derelict]

Topical spironolactone is useless

 

[AndrewBarnes]

Topical spironolactone is useless

How is it useless when it has a higher binding affinity than RU?

 

[BetaBoy]

thought spironolactone needs first pass liver metabolism to get its anti androgenic actives

 

[AndrewBarnes]

thought spironolactone needs first pass liver metabolism to get its anti androgenic actives

That would actually explain a lot. Do you have any links to sources showing topical spironolactone isn't anti androgrnic? I need to do more research

 

[BetaBoy]

That would actually explain a lot. Do you have any links to sources showing topical spironolactone isn't anti androgrnic? I need to do more research

Just read the wiki and looked at the liver metabolites.