I only used Ru for 1 month so i cant say.
All i know is that switching from finasteride to dutasteride for me worked great and really fast. I took it for a few months basically EOD, and i didnt even use minoxidil or proxiphen in this time period, mabye once per week of minoxidil cause i ran out and just didnt bother re-ordering, and i got thickening of existing hair, and some more terminal hairs at the hairline. I could see little hairs in the norwood 0 area that looked like they were going to turn terminal if i stayed on dutasteride and especially if i got back on minoxidil and Proxiphen ( which i just re-started ). I literally didnt care about hairloss and still dont. I was on all types of crazy $#iT in the past, going crazy about hairloss, but dutasteride alone worked faster and better than all of them. So my new regimen is going to be minoxidil foam in the day and night, and proxiphen cream at night after minoxidil foam, and dutasteride EOD.
I got a puffy face, fatigue, some sore joints, and a few abdominal pains from dutasteride, so i stopped about 2 weeks ago. Im going to restart using Milk Thistle every day for liver protection, and use a produc called AIMF which is a natural estrogen inhibitor that works as good as the synthetic drugs. Im pretty sure that the rise in estrogen along with the lack of DHT were the cause of my bloated face, fatigue, and sore joints.