Creatine

persistentone

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KO21

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I was going to start a thread on this.

I've heard before creatine does in fact accelerate hair loss. Anyone else ?
 

dralex

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You completely misread this article. The research being summarized showed that heavy exercise increased inflammatory markers including PGE2. Creatine *DECREASED* the inflammation. Note the word "attenuated".
Agreed, this article states creatine decreases the inflamation. But I have seen a study performed that showed creatine increase DHT by an absurd percentage. Unsure if the study is reliable though.
Heres a link to the study:
https://www.ncbi.nlm.nih.gov/pubmed/19741313

If this study is reliable and you are taking creatine, I would stop taking it ASAP.
 

persistentone

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Agreed, this article states creatine decreases the inflamation. But I have seen a study performed that showed creatine increase DHT by an absurd percentage. Unsure if the study is reliable though.
Heres a link to the study:
https://www.ncbi.nlm.nih.gov/pubmed/19741313

If this study is reliable and you are taking creatine, I would stop taking it ASAP.

That's an interesting study for sure, but how do know the mechanism of action was in fact creatine? Maybe the creatine improved the duration of anaerobic exercise, so the rugby players simply worked out harder? Harder workout and exertion maybe produced more conversion of testosterone to DHT.

I would love to see a better study design, including for example using creatine on non athletes.
 

dralex

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That's an interesting study for sure, but how do know the mechanism of action was in fact creatine? Maybe the creatine improved the duration of anaerobic exercise, so the rugby players simply worked out harder? Harder workout and exertion maybe produced more conversion of testosterone to DHT.

I would love to see a better study design, including for example using creatine on non athletes.
I have no idea how great the study is, but honestly better safe than sorry.
Makes no sense that creatine would improve the duration of anaerobic exercise to the extent that DHT levels would increase 50%. A more long-term study would be useful, but unfortunately that isn't available. Either way, I think creatine is sh*t so I stopped using it long ago anyway (I look way too bloated on the stuff and it doesn't really improve my strength or endurance).
 

persistentone

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I have no idea how great the study is, but honestly better safe than sorry.
Makes no sense that creatine would improve the duration of anaerobic exercise to the extent that DHT levels would increase 50%. A more long-term study would be useful, but unfortunately that isn't available. Either way, I think creatine is sh*t so I stopped using it long ago anyway (I look way too bloated on the stuff and it doesn't really improve my strength or endurance).

It also makes no sense that creatine would affect testosterone or DHT levels. Creatine isn't in this metabolic pathway for testosterone and DHT:

f1-large_[1].jpg


I am personally very sensitive to scalp inflammation. I get a telltale itch whenever I stop treating hair loss. Creatine has never had any discernable effect for me, and I have long periods on and off creatine for many years.

I respect that others will decide to stop creatine based on that study alone. I personally would want to see more studies and understand the mechanism for this result.
 

dralex

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It also makes no sense that creatine would affect testosterone or DHT levels. Creatine isn't in this metabolic pathway for testosterone and DHT:

View attachment 44006

I am personally very sensitive to scalp inflammation. I get a telltale itch whenever I stop treating hair loss. Creatine has never had any discernable effect for me, and I have long periods on and off creatine for many years.

I respect that others will decide to stop creatine based on that study alone. I personally would want to see more studies and understand the mechanism for this result.
I feel ya. If creatine was working wonders for me I wouldn't stop it either because of that one study. Personally, I did not benefit from creatine though so I stopped it before I even saw that study, and seeing that study has made it easy for me to choose to never try creatine again.
Issue is there may not be another study on it for over a decade. This study was from 2009 and I haven't seen a follow up study since.
 

RB1

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Good thing I noticed this thread! I've been using creating for the last 3 months, so hopefully it hasn't created too much hair loss. I've done quite a bit of research in the last 24 hrs (since seeing this thread), and it appears there is a 'good chance' creatine WOULD be detrimental to hair loss. Very unfortunate because I love the stuff, but my hair is more important....
 

Afro_Vacancy

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There's one mediocre study associating creatine with modestly increased DHT.

However, if you're on finasteride, there is no way for creatine to increase your type-II DHT regardless.

Take creatine at will.

Once I switch from cutting to bulking, I'll start using creatine too.
 

RB1

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I'm not on finasteride. Gauging the amount of information I found online regarding 'creatine and balding' - it still seems risky to me....
 

Afro_Vacancy

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I'm not on finasteride. Gauging the amount of information I found online regarding 'creatine and balding' - it still seems risky to me....

You didn't find a lot of information. It's a whole lot of talk emerging from a single mediocre study.
 

RB1

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That's a valid point, but what if there are future studies that prove that there is a correlation?? That would be quite unfortunate for those who have used it for years....
 

Afro_Vacancy

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That's a valid point, but what if there are future studies that prove that there is a correlation?? That would be quite unfortunate for those who have used it for years....

If it ends up demonstrated we'll have to adjust. Right now it's just speculation.
 

RB1

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Yeah but it'll be too late! Hair already history...
 
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