I know of someone on this board who PMed me that he had lots of sides on 1.25. I reminded him (and most people forget this) that he is taking 25% more then the recommended amount. I told him to swtich to 1mg, and he told me it did remove most of his sides but he was scared that 1.25 was more effective then 1mg and didn't want to reduce. I am hoping he listened to me that it makes no difference in efficacy on the quantity of dht blocked.