DID finasteride DO ANYTHING FOR YOUR ANCE?

bubka

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i never had what you would call "acne" though an occasional pimple now and then, like most people, though i don't get as many as i did say in high school and playing football, but still get the occasional one
 

nervx

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finasteride help clear up the little acne i had but after a while it also gave me random outbreaks... nothing too bad though.
 

Strat54

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Propecia cleared my acne completely.
I suffered from cystic acne from the age 16 (now 40). Tried so many antibiotics and topicals and nothing worked until I took propecia and changed to a healthy diet.

I’ve been clear for 8 months, still have oily skin though.
 

HARM1

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Strat54 said:
Propecia cleared my acne completely.
I suffered from cystic acne from the age 16 (now 40). Tried so many antibiotics and topicals and nothing worked until I took propecia and changed to a healthy diet.

I’ve been clear for 8 months, still have oily skin though.
If you still have oily skin I don't think the finasteride was what stopped your acne
 
G

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oily skin isn't necessarily correlated with acne. i always had super dry skin and yet i used to have acne.
 

Bryan

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Finasteride has no effect on sebum production.
 

Strat54

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The only drug that I know that reduces sebum production is Accutane (dangerous) and Vitamin B5 (large doses)

Maybe dermatologists should consider prescribing Finasteride for acne.
I think it has less side effects than Accutane and antibiotics.

At least in my case, antibiotics never cleared completely my acne and gave me three intestine ulcers.
 

HARM1

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Bryan said:
Finasteride has no effect on sebum production.
Coul you explain why you claim thay? is type2 5AR not placed in areas that make sebum?
How do people say it helped thir acne ?
 

Felk

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Many people also say it gave them acne.

Acne is complicated and not just down to sebum.
 

Aplunk1

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Finasteride:

Finasteride was ACCIDENTALLY found to treat male pattern baldness.

Washing your skin produces more sebum.

Finasteride directly affects sebum production.

Side effects are experienced in at least 1/3 individuals.

Finasteride affects the Type II enzyme, located in the brain.



Also, if you're using minoxidil, make sure you use it with Retin-A.

(Edit: Joking, people.)
 

HARM1

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Felk said:
Many people also say it gave them acne.

Acne is complicated and not just down to sebum.
The best acne drug Isotretinoin which comes in for of stuff like Roaccutane takes care of sebum . you could have lots of sebum and no ance due to the amune system being differnet between people. But for someone who has acne it comes down to sebum I belvie.
 

Felk

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HARM1 said:
Felk said:
Many people also say it gave them acne.

Acne is complicated and not just down to sebum.
The best acne drug Isotretinoin which comes in for of stuff like Roaccutane takes care of sebum . you could have lots of sebum and no ance due to the amune system being differnet between people. But for someone who has acne it comes down to sebum I belvie.

I was going to mention that drug. Strangely enough, even though its sort of the oral form of Retin-A (a topical that grows moderate amounts of hair), hair loss is a common side effect.
 

Bryan

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HARM1 said:
Bryan said:
Finasteride has no effect on sebum production.
Coul you explain why you claim thay? is type2 5AR not placed in areas that make sebum?

Nope. Sebaceous glands are rich in the type I form of 5a-reductase. Imperato-McGinley (of "pseudohermaphrodite" fame) specifically tested finasteride for its effect on sebum production several years ago, and found no influence.

HARM1 said:
How do people say it helped thir acne ?

People say all kinds of crap on hairloss forums! :D

Bryan
 

Bryan

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Aplunk1 said:
Finasteride:

Finasteride was ACCIDENTALLY found to treat male pattern baldness.

Washing your skin produces more sebum.

Finasteride directly affects sebum production.

Side effects are experienced in at least 1/3 individuals.

Finasteride affects the Type II enzyme, located in the brain.

Also, if you're using minoxidil, make sure you use it with Retin-A.

(Edit: Joking, people.)

I almost spontaneously combusted, after reading that the first time! :)

Bryan
 

HARM1

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Bryan said:
HARM1 said:
Bryan said:
Finasteride has no effect on sebum production.
Coul you explain why you claim thay? is type2 5AR not placed in areas that make sebum?

Nope. Sebaceous glands are rich in the type I form of 5a-reductase. Imperato-McGinley (of "pseudohermaphrodite" fame) specifically tested finasteride for its effect on sebum production several years ago, and found no influence.

HARM1 said:
How do people say it helped thir acne ?

People say all kinds of crap on hairloss forums! :D

Bryan
What about DHT froM TYPE 2 that gets to the Sebaceous glands VIA the blood ? are there no androgen receptors outside of the cells ?
Is it a fact that Sebaceous glands hacve no type 2?

AND how come the drug inhibiting type 1 that was tested did not help acne? DID it reduce sebum ?
 

Bryan

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HARM1 said:
What about DHT froM TYPE 2 that gets to the Sebaceous glands VIA the blood ?

It obviously had very little effect on sebaceous glands. And now you know why I've been saying for YEARS that serum DHT doesn't have very much effect as an endocrine hormone! :) Once it leaks out of cells into the bloodstream, it's eliminated fairly rapidly.

HARM1 said:
are there no androgen receptors outside of the cells ?

Androgen receptors are proteins that float around the cytoplasm inside cells. Androgens in the bloodstream would have to diffuse through the outer cellular membrane into the interior of the cell, before they could bind with androgen receptors.

HARM1 said:
Is it a fact that Sebaceous glands hacve no type 2?

Not that I know of.

HARM1 said:
AND how come the drug inhibiting type 1 that was tested did not help acne?

Nobody knows the answer to that question.

HARM1 said:
DID it reduce sebum ?

Don't know. It wasn't tested for that, just the overall effect on acne.

Bryan
 

HARM1

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HARM1 said:
AND how come the drug inhibiting type 1 that was tested did not help acne?

Nobody knows the answer to that question.

HARM1 said:
DID it reduce sebum ?

Don't know. It wasn't tested for that, just the overall effect on acne.

Bryan[/quote]
Very intersting, THANKS!
It just may be that thir drug did not work , since I can't seem to see any reason for it not helping acne. maybe DHT isn't the strongest sebum catalyst.
It's stupid that they did not check if it effected sebum , I belive the drug just did not work.

I'm trying to fight my acne as well as my hair loss, what do you think i shoud do ? I use azelic on my face, and i've used roacutne befor which helped. Do you think sods could help combat the imune response?
 
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