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Comparative studies on level of androgens in hair and plasma with premature male-pattern baldness
Hyo-Jung Banga, b, Yoon Jung Yanga, Dong-Seok Lhoa, Won-Yong Leeb, Woo Young Simc and Bong Chul Chung
Abstract
Background: It is well known that male-pattern baldness (male pattern baldness) is not started from occipital, but frontal or scalp of head. We can assume that distribution of androgenic steroids is different for each region of the head. Objective: We hypothesize that the levels of androgenic steroids are different not only between vertex hair with male pattern baldness and controls but also between occipital hair with male pattern baldness and controls.
Results: Our data shows that the levels of DHT and the ratio of testosterone to epitestosterone (T/E ratio) in vertex hair from premature baldness subjects were higher than in that of non-baldness subjects (Fig. 1), whereas the DHT levels and the T/E ratio n occipital hair from the same baldness group were not significantly different. Although the levels of the testosterone in vertex hair was observed no significant difference between the premature balding and the non-balding men, the level of epitestosterone was somewhat lower in the vertex hair of premature baldness subjects than in that of control group.