Do Topicals Like Ru And Cb Give Regrowth?

StudyHacks

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@el_duterino and anyone who's used them

I need regrowth at my temples where there's still hair but now I can see through it and it's pissed me off so f*****g much goddamit

and on my crown

RU is on the way. I'm going to start with 100mg/day so 2ml of the 5% pre-made solution


Also, how stable is the pre-made solution if I immediately put it and store it in the fridge after every use? Does it come in a cool'd box (during the shipping)?
 

Ollie

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Neither will give you the regrowth you’re looking for. Maintenance at very best. If you want regrowth you’d need to use finasteride and hope you’re a good responder.
 

StudyHacks

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Neither will give you the regrowth you’re looking for. Maintenance at very best. If you want regrowth you’d need to use finasteride and hope you’re a good responder.
Isn't RU a stronger anti-androgen than finasteride according to the studies done on RU?
 

Ollie

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Isn't RU a stronger anti-androgen than finasteride according to the studies done on RU?

Complete different method of action and cant really be compared. Reality is topicals for whatever reason dont really work very well. Topical finasteride sort of does because of its flatter line potency but you definitely wont get regrowth with RU or CB especially if you have not great hairloss in your 20's. Anyone who has claimed regrowth from RU was also on minoxidil. I used to use up to 400mg a day of RU (5% solution).
 

StudyHacks

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Complete different method of action and cant really be compared. Reality is topicals for whatever reason dont really work very well. Topical finasteride sort of does because of its flatter line potency but you definitely wont get regrowth with RU or CB especially if you have not great hairloss in your 20's. Anyone who has claimed regrowth from RU was also on minoxidil. I used to use up to 400mg a day of RU (5% solution).
Did it maintain your hair/-line for you? Any sides?
 

Ollie

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Did it maintain your hair/-line for you? Any sides?

It helped maintain for about a year or so but it’s so hard to get it everywhere I ended up just jumping on finasteride. For some reason topicals just aren’t effacious

Had sides on finasteride from raised prolactin which I now manage and have been responding well to finasteride and continue to have thickening and growth all over.
 

StudyHacks

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It helped maintain for about a year or so but it’s so hard to get it everywhere I ended up just jumping on finasteride. For some reason topicals just aren’t effacious

Had sides on finasteride from raised prolactin which I now manage and have been responding well to finasteride and continue to have thickening and growth all over.
how do you manage raised prolactin
 

Ollie

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I have to disagree with Ollie here, although some definitely do not get solid regrowth from Ru Others in fact do, including myself. Also the topical ineffectiveness argument is rather flawed as topical finasteride has produced impressive results, and if I was to take finasteride, which I refuse to do so, I would use a quality topical formulation

Are you only using RU ?
 

Ollie

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OP you can try RU but statistically you'll likely be part of the group who just get maintenance. I should mention i did get 'regrowth' from RU however it was literally 5-6 hairs in my temple and nothing else - so nothing cosmetic. Once you hit NW3 territory you will realise that for most people if you've bothered to make an account on a hair loss forum the worry of taking finasteride will be less than the worry of going bald but only you can decide for yourself.
 

StudyHacks

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I have to disagree with Ollie here, although some definitely do not get solid regrowth from Ru Others in fact do, including myself. Also the topical ineffectiveness argument is rather flawed as topical finasteride has produced impressive results, and if I was to take finasteride, which I refuse to do so, I would use a quality topical formulation
Would it be okay for me to start using 2ml of 5% RU solution so 100mg RU a day, once per day? I find it impossible to get 1ml to cover more than half of my scalp
 

el_duterino

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there is a potential for "limited" regrowth only for the first usage when the loss is very recent - a few months or a year top, maybe, regardless of the drug used

Since most people started RU long after finasteride, like myself, the potential has been long gone by then.

Very few people started RU as their first treatment. Its also true that topical is going to be less effective than oral, and also there are a lot more variables such as hair length, scalp thickness and porosity, vehicle type, powder quality and storage/mixing methods, application methods etc..

Every hair follicle is connected by blood, so if if you get enough drug into the bloodstream you are almost guaranteed to reach every follicle. With topical, iits a blind shot, if the molecule happens to get into the follicle you are lucky, otherwise its just wasted getting absorbed somewhere else. That's why you need a lot more drug for topical than oral.

If you really believe you can regrow hair with anti androgen, you may want to start with oral bicalutamide for a few weeks to get a strong kick out at the earliest stage, then switch to CB for maintenance. BICA is going to give some andro sides for sure, but the drug has been FDA approved and the safety profile is known.

I would not use RU anymore in 2020, this drug still may give you side effects and the safety profile is unknown.. we have better solutions now, Clascoterone aka CB is much safer, but also more expensive.
 
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el_duterino

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I bought it from Kane and I use ethanol 95%
you can add a bit of PG to make it dry slower
 

StudyHacks

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there is a potential for "limited" regrowth only for the first usage when the loss is very recent - a few months or a year top, maybe, regardless of the drug used

Since most people started RU long after finasteride, like myself, the potential has been long gone by then.

Very few people started RU as their first treatment. Its also true that topical is going to be less effective than oral, and also there are a lot more variables such as hair length, scalp thickness and porosity, vehicle type, powder quality and storage/mixing methods, application methods etc..

Every hair follicle is connected by blood, so if if you get enough drug into the bloodstream you are almost guaranteed to reach every follicle. With topical, iits a blind shot, if the molecule happens to get into the follicle you are lucky, otherwise its just wasted getting absorbed somewhere else. That's why you need a lot more drug for topical than oral.

If you really believe you can regrow hair with anti androgen, you may want to start with oral bicalutamide for a few weeks to get a strong kick out at the earliest stage, then switch to CB for maintenance. BICA is going to give some andro sides for sure, but the drug has been FDA approved and the safety profile is known.

I would not use RU anymore in 2020, this drug still may give you side effects and the safety profile is unknown.. we have better solutions now, Clascoterone aka CB is much safer, but also more expensive.
Also, where do you buy CB? There are many vendors on the Internet
 

bluecyclone

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I bought it from Kane and I use ethanol 95%
you can add a bit of PG to make it dry slower
Having used RU and CB can CB keep up with damage from T? I’m using 1% topical Finasteride and losing ground aggressively. Just started RU but think a topical Dutasteride CB Oral
Minoxidil regimen might be the last ditch effort to slow this brush fire.
 

Thinning Sucks

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I tried RU mixed 3.5g in minoxidil for 1.5-2 years - didn’t do anything basically and still slowly kept losing diffuse. I recently dropped it and adding 3 Proscar and 2 dutasteride to minoxidil bottle with some peppermint oil.
 

el_duterino

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I tried RU mixed 3.5g in minoxidil for 1.5-2 years - didn’t do anything basically and still slowly kept losing diffuse. I recently dropped it and adding 3 Proscar and 2 dutasteride to minoxidil bottle with some peppermint oil.

Just Dumping Ru into minoxidil is pretty much guaranteed to not work well. For two reasons, first RU will not dissolve if there is water in the vehicle, even a little bit. Then over time it will degrade in this vehicle.

I have been using RU and now CB for over 10 years, using the following method
- weight the daily amount of powder , for RU 20 to 50mg, for CB you need more as it has no systemic effect
-then mix it with ethanol and a bit of PG (or no PG if you want but it dries fast)
-apply right away..use nitrile gloves to massage the liquid hard before it dries on the scalp.

..this step takes 1 extra minute per day and will guarantee results, as long as hair follicles are healthy enough to start with
 

RobertFord

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Just Dumping Ru into minoxidil is pretty much guaranteed to not work well. For two reasons, first RU will not dissolve if there is water in the vehicle, even a little bit. Then over time it will degrade in this vehicle.

I have been using RU and now CB for over 10 years, using the following method
- weight the daily amount of powder , for RU 20 to 50mg, for CB you need more as it has no systemic effect
-then mix it with ethanol and a bit of PG (or no PG if you want but it dries fast)
-apply right away..use nitrile gloves to massage the liquid hard before it dries on the scalp.

..this step takes 1 extra minute per day and will guarantee results, as long as hair follicles are healthy enough to start with

Hello,

I have bought RU premixed from chemyo and applying 10-20 mg to see if how well I tolerate sides. I do now want to continue this medication since I am scared of it being a non selective androgen, and blocken to much in my body, maybe affecting my heart.

Maybe you have specified how you use CB before but as i interpret it you have made a successfull transition from ru to cb? I want to know where you buy your cb, how many ml you apple and mg? Do you also mix it the same day as ru?

I have followed you and others in ”
The Cb (breezula [clascoterone]) Community Thread”
and there it seems that none of the guys had success with cb, since you are the only one that seems to have succes I would really appreciate if tou could be specific!
Do you btw have a thread where you have written your story with hairloss?

Thankyou for your contribution el duterino
 

el_duterino

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the studies on CB were done using 3ml per day or twice a day, with 7.5% of CB giving the best results. That translates into 225 mg per day, at the current price very few people can afford. Theyused much less and had less results. Also many tried because they failed on finasteride and that is a very hard to succeed group to start.
 
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