dutast bad for you
- Thread starter nawlins99
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nawlins99 said:
It reduces your sperm count (so does finasteride) but usually not by a "clinically significant" level, i.e. not by >30%.
The elevated levels of estradiol are associated with side effects (impotence, low libido, gyno) in a small number of men. The incidence of sides on finasteride and dutasteride is comparable.
Unlike finasteride, dutasteride affects 5AR1 found in brain tissue. Long term effects of this are unknown, but probably not a cause for concern (women have much less 5AR1, I'm not aware of any gender differences in neurological illness).
Slartibartfast
Senior Member
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Yeah, but where's the fun in that?
Original poster - info. about the risks of getting someone pregnant whilst on Avodart is out there if you look for it. Did you run a search on this site to see what has been said previously?
Original poster - info. about the risks of getting someone pregnant whilst on Avodart is out there if you look for it. Did you run a search on this site to see what has been said previously?
antonio666
Senior Member
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flimflam said:I couldn't comment on the effects of dutasteride, but next time - try a bit of research before you blindly stuff mystery pills down your gob eh?
i understand where your coming from filmflam but i would have injected herion into my scalp if it made my hair grow
collegechemistrystudent said:
Not my definition, the one used here.
Effects on male fertility
The effects of dutasteride 0.5mg/day on semen characteristics were evaluated in healthy volunteers aged 18 to 52 (n=27 dutasteride, n=23 placebo) throughout 52 weeks of treatment and 24 weeks of post-treatment follow-up. At 52 weeks, the mean percent reduction from baseline in total sperm count, semen volume and sperm motility were 23%, 26% and 18%, respectively, in the dutasteride group when adjusted for changes from baseline in the placebo group. Sperm concentration and sperm morphology were unaffected. After 24 weeks of follow-up, the mean percent change in total sperm count in the dutasteride group remained 23% lower than baseline. While mean values for all parameters at all time points remained within the normal ranges and did not meet the predefined criteria for a clinically significant change (30%), two subjects in the dutasteride group had decreases in sperm count of greater than 90% from baseline at 52 weeks, with partial recovery at the 24 week follow-up. The possibility of reduced male fertility cannot be excluded.
flimflam
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antonio666 said:flimflam said:I couldn't comment on the effects of dutasteride, but next time - try a bit of research before you blindly stuff mystery pills down your gob eh?
i understand where your coming from filmflam but i would have injected herion into my scalp if it made my hair grow
heh fair point. im being a bit hypocritical anyway, as I've been known to blindly shove mystery substances into my body too
T
Timi
Guest
CCS - In general isn't estrogen good for your hair, testosterone is somewhat bad and DHT is very bad? So wouldn't taking an aromatase inhibitor, that reduces estrogen levels, have negative effects on hair growth? Since male androgens and estrogen compete for the androgen receptors wouldn't reducing the estrogen / androgen ration have negative effects on hair loss?
Prevent99 said:
Well the 5AR deficient pseudohermaphrodites have normal (or slightly elevated) levels of testosterone and still manage to avoid male pattern baldness. And if it comes down to a choice between a modestly negative impact on hair growth from reduced estrogen levels on the one hand, or gyno on the other, I know what I would choose!
[/quote]Well the 5AR deficient pseudohermaphrodites have normal (or slightly elevated) levels of testosterone and still manage to avoid male pattern baldness. And if it comes down to a choice between a modestly negative impact on hair growth from reduced estrogen levels on the one hand, or gyno on the other, I know what I would choose! [/quote]
The 5AR deficient folks did not take anti-estrogens. Their elevated T levels were allowed to aromatize to estrogen at their normal level.
I agree that potentially aggravating hair loss is a much better option than gyno.
[/quote]The 5AR deficient folks did not take anti-estrogens. Their elevated T levels were allowed to aromatize to estrogen at their normal level.
I agree that potentially aggravating hair loss is a much better option than gyno.
Pondle said:Prevent99 said:
Well the 5AR deficient pseudohermaphrodites have normal (or slightly elevated) levels of testosterone and still manage to avoid male pattern baldness. And if it comes down to a choice between a modestly negative impact on hair growth from reduced estrogen levels on the one hand, or gyno on the other, I know what I would choose!
The 5AR deficient folks did not take anti-estrogens. Their elevated T levels were allowed to aromatize to estrogen at their normal level.
I agree that potentially aggravating hair loss is a much better option than gyno.
T
Timi
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purecontrol
Established Member
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Prevent99 said:Pondle said:Prevent99 said:
Well the 5AR deficient pseudohermaphrodites have normal (or slightly elevated) levels of testosterone and still manage to avoid male pattern baldness. And if it comes down to a choice between a modestly negative impact on hair growth from reduced estrogen levels on the one hand, or gyno on the other, I know what I would choose!
The 5AR deficient folks did not take anti-estrogens. Their elevated T levels were allowed to aromatize to estrogen at their normal level.
I agree that potentially aggravating hair loss is a much better option than gyno.
The question there would be if they had high or low levels of estrogen?
I would bet that they would have normal to low levels of estrongen to go along with the low DHT levels, further more I bet they tend to have lower insulin levels and inflamation in general.
purecontrol said:
Purecontrol why would low levels of estrogen correlate with low DHT? Men taking 5ARIs have elevated testosterone and elevated estrogen - this is said to be a very similar hormonal profile to the pseudohermaphrodites. Bryan posted a study that shows how reducing estrogen causes an increase in testosterone and DHT.
I've been on dutasteride's for only 1 month, taking .5mg every 5 days, coupled with 1.25 Proscar. Unfortunately though I am experiencing loss of libido and loss of stamina. I'll get hard, but it won't stay up long. Everything's going fine, then mid session, it's gone. I stopped taking them 1.5 weeks ago, once I realized this was occurring, and I still got issues.
Does anyone have any idea how long my symptoms will last? Or, what I can do to counteract these symptoms? Obviously I could hit up Cialis or something like that, but I'm only 32, so I'm not a fan of that.
Been on propecia or proscar for over 10 years and will continue it.
Does anyone have any idea how long my symptoms will last? Or, what I can do to counteract these symptoms? Obviously I could hit up Cialis or something like that, but I'm only 32, so I'm not a fan of that.
Been on propecia or proscar for over 10 years and will continue it.