Dutasteride equivalent of finasteride 1mg?

[Felk]

Greetings gentlemen,

I've tried to use finasteride twice, but i get weird abdomenal pains, burping, and chest/breast pains from it. The breast pains were accompanied by some fatty nipples (i think) so i obviously stopped it.

I had the same side effects from .5 mg of finasteride, even, which is a shame since I felt a lot better about using finasteride than dutasteride in terms of side effects. I'm also a little worried about shedding at the front, reports of which appear far too often for my comfort.

However I'd used dutasteride at twice a week before for a week or two whilst waiting for finasteride (thanks powersam), and had no such side effects.

Whats the best dosage to mimick Propecia's inhibition of 5AR2? Would dutasteride once per week be the closest I could get to 1mg of finasteride? I'm looking to do something similar to that, not twice a week to get the same inhibition as 5mg of finasteride.

 

[CCS]

yeah, but I'm not sure how constant the levels would stay at that low dose. If you do it you need to take about 5 pills in two days to reach the steady state concentration and then do once a week after that. Otherwise you may metabolise it too fast.

I'd be affraid to do much less than twice a week.

 

[Guest]

well, felk, if dutasteride is giving no side effects, then why not just man up(no offense) and take dutasteride 0.5 mg every day. you will get more regrowth, much better maintenance, etc.

 

[Felk]

yeah, but I'm not sure how constant the levels would stay at that low dose. If you do it you need to take about 5 pills in two days to reach the steady state concentration and then do once a week after that. Otherwise you may metabolise it too fast.

I'd be affraid to do much less than twice a week.

I was under the impression that due to dutasteride's very long half life, once or twice a week dosages were fine, they just worked at a lower level of inhibition. Correct me if I'm wrong. But loading doses always sound a bit iffy to me.

well, felk, if dutasteride is giving no side effects, then why not just man up(no offense) and take dutasteride 0.5 mg every day. you will get more regrowth, much better maintenance, etc.

I have no side effects yet, yes. But i'm 19, dutasteride isn't approved for hair loss, it hasn't been around as long as finasteride, there is no biological model for dutasteride's effects like the pseudos, I don't want to inhibit the type 1 in the brain, etc, etc... I just want to use the lowest dose possible

Also, too many people for my comfort have reported losing hair/thinning at the front from dutasteride, and that's the only place I'm losing it.

 

[Aplunk1]

If you want to imitate finasteride with dutasteride, then you might want to take 2 or 3 capsules a week.

Any more would be superfluous.

I don't think highly of loading doses... I just think it causes more problems, eventually, in its users.

 

[Goingat20]

Hey felk

After taking dutasteride for a while now, ive been thinking and i dont want to keep taking an internal like dutasteride daily. I take it twice a week now. I know people havent had much sides, but im just worried about long term side effects. I think after a week of taking it daily you could just take it 2-3 times a week....

 

[powersam]

bryan said earlier that probably twicE a week was probabLy THE lowest dosE onE coulD take wHILe beinG surE it wasnt too low foR THE half liFE/ BiO aVailaBIltY? NOT SuRE WHaT WORD HE USED.

ps. I HAVE A VIRuS

 

[hair_tomorrow]

About 5 - 6 weeks ago I switched from 1mg finasteride daily to:

1 Dutas every Monday and Thursday,

and 1mg finasteride 3 -4 days per week.

So far it ain't hurt nuttin'.

 

[CCS]

If you want to imitate finasteride with dutasteride, then you might want to take 2 or 3 capsules a week.

Any more would be superfluous.

I don't think highly of loading doses... I just think it causes more problems, eventually, in its users.

3 is much stronger than propecia. It inhibits 95% of typeII and about 15% of type 1. Proscar 5mg inhibits 90% of typeII only. 0.1mg dutasteride per day is the same as 5mg finasteride per day.

 

[blueshard]

hair_tomorrow, if i remember correctly, you were taking some nolva to keep your gyno symptoms at bay. If that is the case, how is that going with the addition of dutasteride?

 

[Goingat20]

Proscar 5mg inhibits 90% of typeII only. 0.1mg dutasteride per day is the same as 5mg finasteride per day.

I think .5mg is equivalent to 5mg for dutasteride a day...

 

[Guest]

Proscar 5mg inhibits 90% of typeII only. 0.1mg dutasteride per day is the same as 5mg finasteride per day.

I think .5mg is equivalent to 5mg for dutasteride a day...

No he's right. 0.1 mg of dutasteride a day is equal to taking a Proscar each day.

 

[Goingat20]

My badd... Didnt think dutasteride was that strong

 

[Fat-Elvis]

Proscar 5mg inhibits 90% of typeII only. 0.1mg dutasteride per day is the same as 5mg finasteride per day.

I think .5mg is equivalent to 5mg for dutasteride a day...

No he's right. 0.1 mg of dutasteride a day is equal to taking a Proscar each day.

um.....so put more simply, 0.1mg of dutasteride is equivalent to 5mg of finasteride?

it's that freakin strong?

 

[powersam]

yes.

 

[Goingat20]

Now i know why after a few years my liver said enough...

 

[Bryan]

um.....so put more simply, 0.1mg of dutasteride is equivalent to 5mg of finasteride?

it's that freakin strong?

Because there seem to be so many misunderstandings about the differences between finasteride and dutasteride and the way they work in the body, I want to drive home one particularly important point: on a simple weight-for-weight basis, dutasteride is about three times more potent than finasteride. So how can only 0.1 mg/day of dutasteride be the equivalent of 5 mg/day of finasteride when that's only 1/50 as much, you ask? Because there's another VERY important aspect of dutasteride which makes it even more effective: it builds-up in the bloodstream over a period of time. Finasteride is eliminated fairly rapidly after you take a dose, but dutasteride stays in your blood for a long time, continuing to build up and build up and build up....and eventually, the sheer QUANTITY of the drug in the bloodstream far exceeds what you get with finasteride.

So dutasteride is so much more powerful than finasteride for two completely different reasons: (1) the dutasteride molecule is inherently three times more potent than the finasteride molecule, and (2) dutasteride levels build-up in the blood much higher than finasteride levels. The bottom-line is that yes, only 0.1 mg/day of dutasteride is the equivalent of 5 mg/day of finasteride.

Bryan

 

[hair_tomorrow]

hair_tomorrow, if i remember correctly, you were taking some nolva to keep your gyno symptoms at bay. If that is the case, how is that going with the addition of dutasteride?

Still taking the nolva. I'm also doing 4 dim+ caps 2x daily so I cut back to 5mg of the nolva daily.

All is well.

 

[Private Ryan]

correct me if i am wrong. but from what i know, finasteride 5mg reduce type II by 70% right? dutasteride 0.1mg also should be around 70% isn't it? where did you get the figure of 90%? is it due to long term use?

http://jcem.endojournals.org/cgi/reprint/89/5/2179.pdf

 

[Guest]

correct me if i am wrong. but from what i know, finasteride 5mg reduce type II by 70% right? dutasteride 0.1mg also should be around 70% isn't it? where did you get the figure of 90%? is it due to long term use?

http://jcem.endojournals.org/cgi/reprint/89/5/2179.pdf

Both are due to long term use. Your reduced DHT levels don't reach a steady state until at least a few weeks on the drugs if not longer. As Bryan said, dutasteride is more potent pill to pill but also because it has a much longer half life.

As for the 5 mg finasteride type II reduction, 5 mg of finasteride reduces type II DHT in the follicles by 90% when it reaches steady state.