Efficacy Of Adding Peppermint Oil To My Minoxidil
- Thread starter mompo
- Start date
I've heard that peppermint oil was found better than minoxidil at regrowing hair, is it not true?
- Reaction score
- 997
Ok
https://www.ncbi.nlm.nih.gov/pubmed/?term=minoxidil+peppermint
Peppermint (Mentha piperita) is a plant native to Europe and has been widely used as a carminative and gastric stimulant worldwide. This plant also has been used in cosmetic formulations as a fragrance component and skin conditioning agent. This study investigated the effect of peppermint oil on hair growth in C57BL/6 mice. The animals were randomized into 4 groups based on different topical applications: saline (SA), jojoba oil (JO), 3% minoxidil (MXD), and 3% peppermint oil (PEO). The hair growth effects of the 4-week topical applications were evaluated in terms of hair growth, histological analysis, enzymatic activity of alkaline phosphatase (ALP), and gene expression of insulin-like growth factor-1 (IGF-1), known bio-markers for the enhanced hair growth. Of the 4 experimental groups, PEO group showed the most prominent hair growth effects; a significant increase in dermal thickness, follicle number, and follicle depth. ALP activity and IGF-1 expression also significantly increased in PEO group. Body weight gain and food efficiency were not significantly different between groups. These results suggest that PEO induces a rapid anagen stage and could be used for a practical agent for hair growth without change of body weight gain and food efficiency
- Reaction score
- 316
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262447/#_=_
Many people tried it since that mouse study, none with success. If it decreases the pge2 it might be because of that.
Many people tried it since that mouse study, none with success. If it decreases the pge2 it might be because of that.
- Reaction score
- 997
"The results showed
that MEO had a potent anti-inflammatory activity in the croton oil-induced
mouse ear edema model, and the possible action mechanism might be attributed
to its inhibitory effect on the production of NO and PGE2."