michael barry
Senior Member
- Reaction score
- 14
Read and learn gents,
http://content.karger.com/ProdukteDB/pr ... =92842.pdf
This is from Intercytex's presentation..................interesting stuff
this is from ICX-EHRS2006:
They use a recipient epidermis from donor A
and dermal cells (DP cells?) from donor B
and put them together in a mouse.
the resulting hair inherits its characteristics from donor A!!!
So, if a dark haired guy gets DP cells from a blond guy, the hair will be dark anyways???
>>>>
P12: A Model for Hair Morphogenesis, J. Qiao, E. Philips, J. Teumer, Intercytex Ltd., Woburn, MA, USA.
In this study, we have developed a model to examine hair morphogenesis. The assay combines an intact donor epidermis with a suspension of dermal cells, which could be from a variety of donors. The epidermis and the dermal cells are applied to a subcutaneous graft
bed created on a dorsal skin flap. When the flap is repositioned over
the graft, the graft is in a subcutaneous position such that it is protected after implantation. The assay is simple to perform and overcomes some of the limitations of other assays for hair induction.
Using the assay, both freshly isolated and cultured dermal cells as
well as cultured dermal papilla cells from several species all induced
hair development. The induced hairs were aesthetically indistinguishable from those of the epidermal donor in length, thickness, and pigmentation, and they were also histologically normal. Time course studies show that the process of hair morphogenesis in the grafts was similar to embryonic hair morphogenesis. In addition to serving as a convenient test for the hair inductive capacity of dermal papilla cells, the assay may also be used to examine specific cellular and molecular interactions during hair morphogenesis, such as epithelialmesenchymal interactions and melanogenesis
http://content.karger.com/ProdukteDB/pr ... =92842.pdf
This is from Intercytex's presentation..................interesting stuff
this is from ICX-EHRS2006:
They use a recipient epidermis from donor A
and dermal cells (DP cells?) from donor B
and put them together in a mouse.
the resulting hair inherits its characteristics from donor A!!!
So, if a dark haired guy gets DP cells from a blond guy, the hair will be dark anyways???
>>>>
P12: A Model for Hair Morphogenesis, J. Qiao, E. Philips, J. Teumer, Intercytex Ltd., Woburn, MA, USA.
In this study, we have developed a model to examine hair morphogenesis. The assay combines an intact donor epidermis with a suspension of dermal cells, which could be from a variety of donors. The epidermis and the dermal cells are applied to a subcutaneous graft
bed created on a dorsal skin flap. When the flap is repositioned over
the graft, the graft is in a subcutaneous position such that it is protected after implantation. The assay is simple to perform and overcomes some of the limitations of other assays for hair induction.
Using the assay, both freshly isolated and cultured dermal cells as
well as cultured dermal papilla cells from several species all induced
hair development. The induced hairs were aesthetically indistinguishable from those of the epidermal donor in length, thickness, and pigmentation, and they were also histologically normal. Time course studies show that the process of hair morphogenesis in the grafts was similar to embryonic hair morphogenesis. In addition to serving as a convenient test for the hair inductive capacity of dermal papilla cells, the assay may also be used to examine specific cellular and molecular interactions during hair morphogenesis, such as epithelialmesenchymal interactions and melanogenesis