flux
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Found this in another forum where a few members have it in their mind to make a home brew version (though the task appears daunting, some good information was provided by the patent app). Very interesting stuff!
http://l2.espacenet.com/espacenet/viewe ... =en&DB=EPD
Click on the "Desc" button to see the Patent
This section of the forum should be more active, for sure.
An excerpt pointed out on the other forum by Androgen:
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Example 16
Effect of Hair Cycle Stage
Skin explants from mice during telogen at 3 weeks of age were cultured for 72 hours, in the presence of proteasome inhibitors, and then the explants were histologically examined. In the untreated control explants, the follicles were few and small. In the explants treated with PSI (50 nM), epoxomicin (25 nM), and the hybrid
PSI-epoxide (50 nM), there was an obvious increase in hair follicle diameter, and follicle elongation. Minoxidil also caused these changes, but at concentrations 10, 000-fold greater. Since these small follicles resemble the miniaturized follicles seen in male pattern baldness, this suggests these compounds may have the same effects in that situation.
_____
Results in three weeks !? Far beyond that of minoxidil !? These were on mice, so it is unsure what the results in humans will be. I'm trying not to keep my hopes up, but its hard not to!
http://l2.espacenet.com/espacenet/viewe ... =en&DB=EPD
Click on the "Desc" button to see the Patent
This section of the forum should be more active, for sure.
An excerpt pointed out on the other forum by Androgen:
_____
Example 16
Effect of Hair Cycle Stage
Skin explants from mice during telogen at 3 weeks of age were cultured for 72 hours, in the presence of proteasome inhibitors, and then the explants were histologically examined. In the untreated control explants, the follicles were few and small. In the explants treated with PSI (50 nM), epoxomicin (25 nM), and the hybrid
PSI-epoxide (50 nM), there was an obvious increase in hair follicle diameter, and follicle elongation. Minoxidil also caused these changes, but at concentrations 10, 000-fold greater. Since these small follicles resemble the miniaturized follicles seen in male pattern baldness, this suggests these compounds may have the same effects in that situation.
_____
Results in three weeks !? Far beyond that of minoxidil !? These were on mice, so it is unsure what the results in humans will be. I'm trying not to keep my hopes up, but its hard not to!
