I used to be afraid of this too. Yes, stay away from direct fan when you put minoxidil on. What I think is that since minoxidil takes hour to enter your skin entirely, if you sit in front of a fan and dry it up then certainly it doesn't go into your skin then? So I rather be safe than sorry and stay away from fans. BTW, I have no proof of this and never read anything confirming my thoughts, it's just something I thought of back in the day.