father a child while on avodart ?

[deth]

Hi,

I know this has been discussed several times but
there wasn't a clear answer to that particular question
I think. I know that it is FDA approved that there's only a very
small chance that your semen will badly effect an embryo which is
already fathered. So it's maybe ok to do it with a pregnant woman.

But I think there's no answer about the topic, because I didn't find
anything (reliable) on
the net about it. I know that with propecia there's
all ok.

I don't think the ejaculat volume, the slight higher chance for impotence
or the gyno are the problem the $#!t is:



Dutasteride is highly bound to proteins in human semen (>96%), potentially reducing the amount of dutasteride available for vaginal absorption.

http://www.avodart.com/m07_06.html#text22

I don't get this statement, isn't it contradictorily ?


I know dutasterid is in the sperms an this is the bad thing about it.
I guess it's also the reason why it isn't FDA approved against hair loss.

 

[IBM]

why not adopt children instead?

 

[oni]

IBM is sooo correct.......................................... please adopt IBM.

I think IBM needs all the love and special care a family can give......................................

 

[Pondle]

"Small amounts of dutasteride have been recovered from the semen in subjects receiving Avodart 0.5mg day. Based on studies in animals, it is unlikely that a male foetus will be adversely affected if his mother is exposed to the semen of a patient being treated with Avodart (the risk of which is greatest during the first 16 weeks of pregnancy)."

"The effects of dutasteride 0.5mg/day on semen characteristics were evaluated in healthy volunteers aged 18 to 52 (n=27 dutasteride, n=23 placebo) throughout 52 weeks of treatment and 24 weeks of post-treatment follow-up. At 52 weeks, the mean percent reduction from baseline in total sperm count, semen volume and sperm motility were 23%, 26% and 18%, respectively, in the dutasteride group when adjusted for changes from baseline in the placebo group. Sperm concentration and sperm morphology were unaffected. After 24 weeks of follow-up, the mean percent change in total sperm count in the dutasteride group remained 23% lower than baseline. While mean values for all parameters at all time points remained within the normal ranges and did not meet the predefined criteria for a clinically significant change (30%), two subjects in the dutasteride group had decreases in sperm count of greater than 90% from baseline at 52 weeks, with partial recovery at the 24 week follow-up. The possibility of reduced male fertility cannot be excluded."

http://emc.medicines.org.uk/