Follica News (small Molecule Aplify New Hair Growth) - Annual Report And Accounts - Puretech Health

Left4bald

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News from Puretech Health

(Follica findings a Small molecule shown to amplify new hair growth during healing.
100 new hairs

Short-term use, systemically safe options identified Near-term clinical development of a “game changing” platformFuture pipeline to further amplify effect)

" Enabling follicle neogenesis and skin rejuvenation through immune response to wounding
Founded by PureTech Health, Follica’s regenerative biology platform is based on seminal findings from the University of Pennsylvania that demonstrated the creation of skin organs (hair follicles) in adult mammals after abrasion.

This technology is being applied to treat androgenetic alopecia and other aesthetic-related indications.

Follica’s technology is the first, to PureTech’s knowledge, designed to create new follicles and hair through disruption of the skin, followed by treatment to enhance the effect.

Follica completed three human clinical studies of patients with androgenetic alopecia to demonstrate hair growth and new hair follicle formation and has been optimising its device and conducting tests in androgenetic alopecia and other aesthetic indications.

Follica has preclinical data which show the potential for next-generation proprietary compounds to further enhance the effect of new hair follicle formation.

Follica completed its clinical-stage development of a next-generation device and drug combination product for androgenetic alopecia, which is currently in an optimisation study.

Further phases of preclinical testing are also ongoing towards the prioritisation and development of next-generation, proprietary compounds based on Follica’s intellectual property.

Follica’s pivotal study is expected to commence following the completion of the optimisation study." (always the same words)
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tomJ

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News from Puretech Health

(Follica findings a Small molecule shown to amplify new hair growth during healing.
100 new hairs

Short-term use, systemically safe options identified Near-term clinical development of a “game changing” platformFuture pipeline to further amplify effect)

" Enabling follicle neogenesis and skin rejuvenation through immune response to wounding
Founded by PureTech Health, Follica’s regenerative biology platform is based on seminal findings from the University of Pennsylvania that demonstrated the creation of skin organs (hair follicles) in adult mammals after abrasion.

This technology is being applied to treat androgenetic alopecia and other aesthetic-related indications.

Follica’s technology is the first, to PureTech’s knowledge, designed to create new follicles and hair through disruption of the skin, followed by treatment to enhance the effect.

Follica completed three human clinical studies of patients with androgenetic alopecia to demonstrate hair growth and new hair follicle formation and has been optimising its device and conducting tests in androgenetic alopecia and other aesthetic indications.

Follica has preclinical data which show the potential for next-generation proprietary compounds to further enhance the effect of new hair follicle formation.

Follica completed its clinical-stage development of a next-generation device and drug combination product for androgenetic alopecia, which is currently in an optimisation study.

Further phases of preclinical testing are also ongoing towards the prioritisation and development of next-generation, proprietary compounds based on Follica’s intellectual property.

Follica’s pivotal study is expected to commence following the completion of the optimisation study." (always the same words)
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Hi good find! Where can we find this info?
 

NotInmywatch

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kiwi666

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Good question ! I think 1 year at least... 2 maybe ? Don't know, just a thought...

I think about SM with Follica . It would be a good option .
Very cool.

This adds a lot of much needed hard science to the needling and healing factors conversation.

I’m no scientist but I think it supports the argument that wounding alone isn’t going to cut the mustard for most people - despite it being enough for some people.
 

champpy

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Haven't they been "optimizing" this product for the past two years or am I thinking of another company
I'm also tired of the use of the term pivotal when referring to a phase of testing. Every phase of testing is pivotal.
 

kiwi666

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No. These guys have been quiet for years. Are you thinking Histogen?

My understanding is that pivotal is being used in the business sense.

They have proved it is safe and they have proved at some level it works. Now they have to go through another level of FDA approval and get ready to commercialise it.
 

Rolandconil

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About 100 new hair they have already written. 100 new ones. 25 of them are terminal. It seems to be a game with investors.
 

NotInmywatch

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How deep do they wound and how many sessions ....
 

Ryko

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I don't understand, is this microneedling or some other type of wounding? Also, what do they mean by "new hairs" is it new follicles or just reviving miniaturized hairs?
 

Bill_Russo

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Indeed. While this is good to hear, it sounds like it is indeed a couple or years or more away from materializing, if it does materialize at all. Let's hope it does, along with RCH-01... some could have a chance at giving the ultimate cockslap to this hair loss bullshit with those two!
 

Jakejr

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Those are the deepest wounds I’ve ever seen. They’re not kidding about wounding the scalp.
 

MeDK

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Expected Milestones and Timing
  • Follica expects to initiate the pivotal study in androgenetic alopecia following completion of an ongoing optimization study in the first half of 2019.
So there should be some more updates about the study in this year.
 

soull

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Indeed. While this is good to hear, it sounds like it is indeed a couple or years or more away from materializing, if it does materialize at all. Let's hope it does, along with RCH-01... some could have a chance at giving the ultimate cockslap to this hair loss bullshit with those two!

Hola amigo.

The blow that many can give is the recovery of miniaturizedhair, if my miniaturized hair is recovered my appearance wouldbe more or less normal hahaha
 
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