Gluten Free diet got rid of the Niacin Flush

[Gold Top]

Many years ago I tried a health supplement called Niacin (Vitamin B3) which used to give me a Niacin Flush/Rash. Then about 4 years ago I was diagnosed with Celiac Disease and started a strict Gluten Free diet.

Recently I tried taking Niacin again and was surprised to find that it didn't give me a rash, not even when taking 2 x 250mg/1500% RDA a day. I've read that Niacin Flush is caused when Niacin reacts with receptors in the body called PD1 receptors, so perhaps the Gluten Free diet is reducing the activity of these PD1 receptors.

Has anybody else tried taking Niacin either before or after starting a Gluten Free diet? It would be interesting to hear if anyone else has found that a Gluten Free diet prevents Niacin Flush.

 

[Dench57]

I've heard both Niacin flushing and Gluten free diet are generally good for hair/scalp and reducing the inflammatory component of male pattern baldness. I just ordered some Niacin so will be doing my first "flush" tonight just for a laugh, see if it helps my scalp pain. male pattern baldness sufferers who've switched to gluten free often say it helped their "male pattern baldness itch".

 

[Gold Top]

How does this relate to hair loss though? Im not too knowledgeable about hair loss, so I dont know what PD1 receptors do.

I think over-active PD-1 receptors are somehow involved in hair loss.

I know that Niacin can improve circulation to the scalp. I found a website that says it's 'structurally related' to Minoxidil:

http://www.hairloss-research.org/Niacin6-11.html

 

[Gold Top]

My doctor recently tested me and I was vitamin and nutrition deficient in a lot of things.. I have a lot of vitamin supplements now, and I heard that apparently a wheat gluten dairy free diet helps the absorption of these vitamins.

Wheat or Gluten can sometimes damage the lining of the stomach and intestine which then prevents the body absorbing nutrients. Shortly after being diagnosed with Celiac Disease I was told that I had Osteopenia (a bone thinning condition) because I wan't absorbing Vitamin D. My Iron levels were also low.

 

[Gold Top]

Vitamin D from the sun works better.

Thanks. The Vitamin D I'm taking is Vitamin D3 which is supposed to be the same as the type made by sunlight.

I've also started taking a Healthy Origins Vitamin E/Tocotrienol complex after reading this:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819075/

Celiac Disease and Nutrient Deficiancy:
http://drlisawatson.com/nutrient-deficiencies-celiac

Article about Gluten:
https://translate.google.co.uk/tran...article/8709-Gluten-le-tueur-cache&edit-text=

Niacin reduces DHT:
http://niacinflushing.blogspot.co.uk/2011/10/how-i-used-niacin-to-grow-back-my-hair.html

I found this article about a type of PD-1 cell called a PD-L1 cell:
http://www.nature.com/jid/journal/v134/n3/full/jid2013368a.html

"PD-L1 might represent a unique HF expressed factor conferring IP with a potential role in inflammatory hair loss, autoimmune diseases, and graft rejection."