Interesting Global. If your DHT levels were reduced, by let's say 92 percent, you had a DHT level of roughly 7.75 before taking dutasteride.
That's out of the normal range by quite a bit. Tells me something about us male pattern baldness sufferers! :-x
Your testosterone levels were probably at the lower end of the acceptable range also? Hmmm....?
Less testosterone, more DHT? Hmmm....?
Friggin" male pattern baldness!! :cry:
I want my testosterone back!! :-x
Harie, why wouldn't he want the testosterone level of a 25 year old rather than the normal level of a 39 year old? :wink:
Tidbit quote from Dr. Sahelian regarding declining levels of testosterone in men nowadays. (Could this be why men are experiencing more male pattern baldness at younger ages?):
Testosterone levels lower in men
There has been a drop in U.S. men's testosterone levels since the 1980s. The average testosterone level dropped by 1 percent a year, Dr. Thomas Travison and colleagues from the New England Research Institutes in Watertown, Massachusetts, found. This means that, for example, a 65-year-old man in 2002 would have testosterone levels 15 percent lower than those of a 65-year-old in 1987. This also means that a greater proportion of men in 2002 would have had below-normal testosterone levels than in 1987. Travison and his team analyzed data from the Massachusetts Male Aging Study, a long-term investigation of aging in about 1,700 Boston-area men. Data from the men were collected for three time intervals: 1987-1989, 1995-1997, and 2002-2004. While a man's testosterone level will fall steadily as he ages, the researchers observed a speedier decline in average testosterone levels than would have been expected with aging alone. They hypothesized that the rising prevalence of obesity as well as the sharp decline in cigarette smoking might help explain their findings, given that testosterone levels are lower among overweight people and smoking increases testosterone levels. But these factors accounted for only a small percentage of the observed difference. It's likely that some sort of environmental exposure is responsible for the testosterone decline. Journal of Clinical Endocrinology and Metabolism, January 2007
Of course, I'm assuming your body compensates by producing more DHT. This is an opinion by a total layman though!!
Nope, I"M WRONG:
102. Transdermal testosterone therapy in the treatment of male hypogonadism.
Ahmed SR, Boucher AE, Manni A, Santen RJ, Bartholomew M, Demers LM
Department of Medicine, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
J Clin Endocrinol Metab 1988 Mar;66(3):546-51
Five hypogonadal men were treated with transdermal testosterone therapy, using a testosterone patch applied to the scrotal skin. Daily application of the patch, which contained 10 mg testosterone, produced an increase in serum testosterone concentrations from a pretreatment value of 45 +/- 12 (+/- SE; 1.5 +/- 0.4) to 436 +/- 80 ng/dL (15.1 +/- 2.8 nmol/L; P less than 0.001) after 4 weeks of treatment. Normal serum testosterone concentrations were achieved in all men after 6-8 weeks of therapy and were maintained during continued long term therapy for 9-12 months with a patch containing 15 mg testosterone. All men reported a subjective increase in libido and sexual function during therapy, and three men preferred it to testosterone injections. The serum testosterone and estradiol levels did not rise above the normal adult male range at any time during therapy. However, elevated serum dihydrotestosterone (DHT) concentrations occurred during treatment; the pretreatment DHT concentration was 95 +/- 3 ng/dL (3.3 +/- 0.1 nmol/L), and it increased to 228 +/- 40 ng/dL (7.8 +/- 1.4 nmol/L) after 4 weeks of treatment and remained elevated thereafter. The individual mean DHT to testosterone ratio increased from a pretreatment value of 0.2 (range, 0.1-0.3) to 0.6 (range, 0.4-0.7) after 2 weeks of therapy and remained high thereafter. Comparison of the serum DHT levels in patients during therapy with those in normal men who had similar testosterone concentrations [531 +/- 62 vs. 566 +/- 72 ng/dL (18.4 +/- 2.1 vs. 19.6 +/- 2.5 nmol/L); P greater than 0.05] revealed that the mean serum DHT concentration was significantly higher in the patients [315 +/- 69 vs. 87 +/- 6 ng/dL (10.8 +/- 2.4 vs. 2.9 +/- 0.2 nmol/L); P less than 0.001], as was the mean DHT to testosterone ratio [0.6 (range, 0.25- 1.1) vs. 0.16 (range, 0.09- 0.24); P less than 0.001]. The high serum DHT levels presumably were due to increased metabolism of testosterone to DHT by the 5 alpha-reductase in the scrotal skin. Serum 3 alpha-androstanediol glucuronide levels were not elevated in the patients. We conclude that transdermal testosterone therapy is an effective long term treatment for hypogonadism in men. It is, however, associated with high serum DHT levels, whose potential long term effects on the prostate and other tissues need to be investigated.
Another wacko Old Baldy, layman theory put to rest!! :2gunsfiring_v1:
Friggin' male pattern baldness. God da**it!!!