Cassin
Senior Member
- Reaction score
- 78
Intersting comment made by Dr Pickart on his site. I have never heard what hair growth results you can specifically expect from Copper-Peptides until now.
It seem like the results are a little better than minoxidil 2% were you to simulate this vaguely mentioned study. Unforunately we don't know what % of CP's they used or how frequently they applied it in this study.
For the FDA studies they used 2.5% & 1.5%, and 2.5% was the winner. Apparantly the dark blue color and irritation were problems in the FDA studies. We also know that Folligen, Tricomin and American Crew use less than 1% in their formulas.
So with what is available to us in current concentrations, it would seem like CP's are mainly usefull to repair some of the damage done to our scalp via minoxidil or other topicals. Not that I ever expected regrowth from it, in fact I have never had much faith in that. It's just interesting getting verification from the inventor of the product. I was a bit dissapointed. But it still has a lot more science backing it than allot of other junk we use.
Anyway......the write up.
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Hair retention & growth stimulation
In 1985, a series of GHK-Cu analogues with added hydrophobic residues (fatty acids or hydrophobic amino acids) was found to stimulate hair growth strongly around healing wounds in mice. It was possible to obtain striking increases in hair follicle size and the rate of localised hair growth in mice.
Later, Hideo Uno and colleagues at the University of Wisconsin reported that these copper complexes produced a stimulation of the follicular cell proliferation, resulting in an enlargement of the anagen follicles, and converted vellus hair into terminal hair. GHK-Cu analogues also minimised hair loss after experimental chemotherapy in rats and accelerated new hair growth. These actions on hair growth may be secondary to improvements in skin vitality that increase nutrient flow to hair follicles.16
In humans, the results are less striking but do exist. An unpublished study by ProCyte reported that one GHK-Cu analogue increased terminal hair growth in adult men approximately 30% more than was reported for the control substance (2% minoxidil). GHK-Cu has been shown to increase hair outgrowth from hair transplants in men.17
http://www.skinbiology.com/specchem.html
It seem like the results are a little better than minoxidil 2% were you to simulate this vaguely mentioned study. Unforunately we don't know what % of CP's they used or how frequently they applied it in this study.
For the FDA studies they used 2.5% & 1.5%, and 2.5% was the winner. Apparantly the dark blue color and irritation were problems in the FDA studies. We also know that Folligen, Tricomin and American Crew use less than 1% in their formulas.
So with what is available to us in current concentrations, it would seem like CP's are mainly usefull to repair some of the damage done to our scalp via minoxidil or other topicals. Not that I ever expected regrowth from it, in fact I have never had much faith in that. It's just interesting getting verification from the inventor of the product. I was a bit dissapointed. But it still has a lot more science backing it than allot of other junk we use.
Anyway......the write up.
**************************************************
Hair retention & growth stimulation
In 1985, a series of GHK-Cu analogues with added hydrophobic residues (fatty acids or hydrophobic amino acids) was found to stimulate hair growth strongly around healing wounds in mice. It was possible to obtain striking increases in hair follicle size and the rate of localised hair growth in mice.
Later, Hideo Uno and colleagues at the University of Wisconsin reported that these copper complexes produced a stimulation of the follicular cell proliferation, resulting in an enlargement of the anagen follicles, and converted vellus hair into terminal hair. GHK-Cu analogues also minimised hair loss after experimental chemotherapy in rats and accelerated new hair growth. These actions on hair growth may be secondary to improvements in skin vitality that increase nutrient flow to hair follicles.16
In humans, the results are less striking but do exist. An unpublished study by ProCyte reported that one GHK-Cu analogue increased terminal hair growth in adult men approximately 30% more than was reported for the control substance (2% minoxidil). GHK-Cu has been shown to increase hair outgrowth from hair transplants in men.17
http://www.skinbiology.com/specchem.html