Half life of Propecia
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socks
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Half-life: The time required for half the quantity of a drug or other substance deposited in a living organism to be metabolized or eliminated by normal biological processes.
The mean terminal half-life for Finasteride is approximately 5-6 hours in men 18-60 years of age and 8 hours in men more than 70 years of age. Within 24hours of taking Finasteride there is a 65% decrease in DHT serum levels. Testosterone and estradiol are increased by approximately 15% (as compared to baseline).
Finasteride works by inhibiting the Type II 5ar enzyme which is responsible for converting testosterone into DHT. While there are two enzymes that convert testosterone into DHT, the Type II 5ar is the primary enzyme inside the hair follicle cell (where the damage from androgenetic alopecia takes place).
By lowering the levels of DHT in your hair follicle cell the process of androgenetic alopecia is halted or slowed; Some regrowth may even result.
It is important to note that the half-life of Finasteride in not the only factor when it comes keeping DHT levels suppressed! Once the Type II 5ar enzyme is inhibited by one dose of Finasteride it can take over 2 weeks for your DHT levels to return to normal. This is because the Type II 5ar enzyme has a slow "turn-over" rate.
Generally speaking, most men tolerate Finasteride very well and the official occurrence of negative side-effects is 2%.
The mean terminal half-life for Finasteride is approximately 5-6 hours in men 18-60 years of age and 8 hours in men more than 70 years of age. Within 24hours of taking Finasteride there is a 65% decrease in DHT serum levels. Testosterone and estradiol are increased by approximately 15% (as compared to baseline).
Finasteride works by inhibiting the Type II 5ar enzyme which is responsible for converting testosterone into DHT. While there are two enzymes that convert testosterone into DHT, the Type II 5ar is the primary enzyme inside the hair follicle cell (where the damage from androgenetic alopecia takes place).
By lowering the levels of DHT in your hair follicle cell the process of androgenetic alopecia is halted or slowed; Some regrowth may even result.
It is important to note that the half-life of Finasteride in not the only factor when it comes keeping DHT levels suppressed! Once the Type II 5ar enzyme is inhibited by one dose of Finasteride it can take over 2 weeks for your DHT levels to return to normal. This is because the Type II 5ar enzyme has a slow "turn-over" rate.
Generally speaking, most men tolerate Finasteride very well and the official occurrence of negative side-effects is 2%.