I flew the day after surgery which people recommend due to swelling, however I did not experience any swelling. Personally, if I had to do it again, I'd stay local as long as possible then travel. Each day your grafts get more and more set up to day 10. If you can chill in the area for 5-7 days postop, it may be ideal.
There is mild donor area pain, and you feel like you are wearing a helmet on your head for the first few days, but there is no significant discomfort.