https://cunninghamclinicstore.com/product/biote-hair-rescue-activate

[bekeero]

Admin
What is your evaluation of this product, peptide, PTD-DBM, the active ingredient in the treatment of baldness?

Biote Hair Rescue: Activate - Fast Shipping & Excellent Prices

Biote Hair Rescue: Activate combines potent peptides and vanilla methylate to stimulate hair growth. Thicker, fuller hair in as little as five weeks!

cunninghamclinicstore.com

 

[Trichosan]

The price they list is pretty good (depending on the concentration in their 2oz)

Some information from another supplier:

PTD.-DBM is a topical hair product which helps activate the Wnt-Beta-catenin pathway via inhibition of CXXC5. This articular pathway has been proven to help rescue DHT induced hair follicle miniaturization. CXXC-type zinc finger protein 5 (CXXC5) is a negative
regulator of the Wnt/β-catenin pathway which has been associated with hair restoration and wound healing. Follicle development and
formation can impeded by CXXC5 binding with the protein Dishevelled. PTD-DBM is a very recently created peptide which interferes with the binding process of CXXC5 and Dishevelled. Studies have proven that PTD-DBM is
significantly more effective at inducing hair neogenesis when combined with Valproic Acid, which stimulates the Wnt/β-catenin pathway when applied topically. This combination should be applied post-microneedling to take advantage of the follicle development that is induced
naturally by the wound healing process.

 

[CastorTroy]

I will be a guinea pig here I will use 2 bottles per month of this for a few months and will update any changes...

 

[charlie76761]

Great find OP. I think I'll trial also. More info on one the molecules below. Bit surprised it's commercialized already - anyone know much of the brand now selling it, BioTE?

PTD-DBM Update: Q&A With Dr. Kang-Yell Choi - Follicle Thought

2021 Q&A With Dr. Kang-Yell Choi: Update (9/14/21) I was recently able to conduct another Q&A with Dr. Kang-Yell Choi who gives the latest updates on his company below. Among the updates, Dr. Choi’s startup aimed at commercializing drugs which target the CXXC5 protein is now going by a new name...

www.folliclethought.com

 

[pegasus2]

The concentration is too low, and it's not absorbed without microneedling. It's also pretty unstable. The company that developed it is testing a drug called KY19382 to replace it.

 

[inmyhead]

How did they manage to get this? Isn't that thing patented or smth?

 

[pegasus2]

Talked to a guy on reddit. His GF is a biochemical engineer. She synthesized it for him. Have you managed to find a source for it Pegasus?

Nope

 

[LouisSarkozy]

any skin sides with ptd-dbm? i'm seeing a lot of clinic offering it lately alongside methyl vanillate or vpa for wnt / ghk-cu and tb 500/ zinc thymuline . maybe it could be a decent combination replacement for those that can't habdle minoxidil due to skin sides