All I can tell you is 10 years worth of personal experience.
- After 10 years on Revivogen I have never had any systematic sides
- After 2 months of spironolactone, I felt the onset of gyno. Not the full blown type, just a swelling of the chest accompanied by a dull pain. I stopped the spironolactone and the pain and swelling went away within 4 weeks and I was back to normal. I started again 3 months later to make sure with same result.
- Don't use this as a reason not to take it, I'M prone to this type of side effect. Bottom line is, if you notice any side effects just stop taking it and IMO and experience, will b back to normal in as long as you've been on it.