Kintor new AR degrader w/o side effects

[FollicleGuardian]

Kintor Pharmaceuticals just got their IND application for their new drug GT20029 approved by the NMPA.

What is GT20029?

«GT20029 is an AR degrader that degrades the AR protein. The mechanism of action of GT20029 is to recruit the AR protein to the E3 ubiquitin ligase for degradation. It acts on the local tissues of the peripheral skin and local hair follicle sebaceous glands, which reduces the sensitivity of AR to androgens without systemic exposure to the drug.»

http://gamma.euroland.com/tools/ch/?app=news&at=ATTOPEN&oid=3868135&l=EN&na=ami062@uit.no&ru=http://asia.tools.euroland.com/tools/subscriptioncentre2/tracker/attachment/?atid=1280030&url=SG9uZ0tvbmdcRXRuZXRcMjAyMS0wMlxIS0VYLUVQU18yMDIxMDIwMV85NjA4ODg5XzAuUERG&companycode=KY-9939&isstockexchangerelease=1

 

[Pls_NW-1]

Kintor Pharmaceuticals just got their IND application for their new drug GT20029 approved by the NMPA.

What is GT20029?

«GT20029 is an AR degrader that degrades the AR protein. The mechanism of action of GT20029 is to recruit the AR protein to the E3 ubiquitin ligase for degradation. It acts on the local tissues of the peripheral skin and local hair follicle sebaceous glands, which reduces the sensitivity of AR to androgens without systemic exposure to the drug.»

http://gamma.euroland.com/tools/ch/?app=news&at=ATTOPEN&oid=3868135&l=EN&na=ami062@uit.no&ru=http://asia.tools.euroland.com/tools/subscriptioncentre2/tracker/attachment/?atid=1280030&url=SG9uZ0tvbmdcRXRuZXRcMjAyMS0wMlxIS0VYLUVQU18yMDIxMDIwMV85NjA4ODg5XzAuUERG&companycode=KY-9939&isstockexchangerelease=1

Wow thats crazy. So this is even much better than Breezul. Right?

 

[FollicleGuardian]

Wow thats crazy. So this is even much better than Breezul. Right?

It will outperform Breezula by a mile

 

[Pls_NW-1]

It will outperform Breezula by a mile

When is this going to be out!? Sounds like daro, or? Can someone compare it to other Anti Androgens?

 

[Pls_NW-1]

If finasteride + bica + this + maybe spironolactone/cypro won't halt my loss, I would be afraid. Lol

 

[Frenchboy]

Sounds cool.
They precise that is entering to "clinical stage", it means that the pre-clinical stage is already done ? No need to wait 2-3 years as usual before to see the stage 1 starting ?

Hope this decade will see the development of AR without side effets.

 

[Frenchboy]

Could this be IT?

Funny, I had a strange feeling today before I opened the forum unlike the other 383984934938743 times where I opened it hoping that THIS TIME I will see a thread saying finally the cure is here.

IS THIS IT?

Hair transplant + THIS= CURE?

Haha would love to say that. Let's wait for the results when the phase I will be out. 1 year minimum.

 

[Selb]

This is interesting because it would counter upregulation or age related AR sensitivity. Reminds me of Dimethylcurcumin

 

[Frenchboy]

Moreover, they precise that the results come "quicker" than the others AR regultator. Can't wait to know more.

 

[Shush]

They are looking serious. Surprisingly moving fast forward. Fingers crossed. At the end of the day a safe mainteneance drug is all we need considering the excellent results of today's hair transplants

 

[Tom4362]

It will outperform Breezula by a mile

How would you know?

 

[Zon Ama]

Sounds cool.
They precise that is entering to "clinical stage", it means that the pre-clinical stage is already done ? No need to wait 2-3 years as usual before to see the stage 1 starting ?

Hope this decade will see the development of AR without side effets.

Seems to be the case.

 

[whatevr]

 

[Pls_NW-1]

The side effects you get from AA are actually the effects of them, which you actually want. If you really want to preserve your hair you most likely will need estrogen dominance. Thats just FACCTS lol

 

[Isneezedsohard]

This looks DOPE

 

[whatevr]

The side effects you get from AA are actually the effects of them, which you actually want. If you really want to preserve your hair you most likely will need estrogen dominance. Thats just FACCTS lol

Not sure why we'd have to accept that garbage. NW1 men aren't walking around with b**ch tits, libidoless and moody. A proper drug will only castrate your scalp and nothing else. Them's the breaks.

 

[Isneezedsohard]

Not sure why we'd have to accept that garbage. NW1 men aren't walking around with b**ch tits, libidoless and moody. A proper drug will only castrate your scalp and nothing else. Them's the breaks.

That's the dream right there. That's why I think Duta mesotherapy is so promising. Too bad no one f*****g does it in the US

 

[Pls_NW-1]

Not sure why we'd have to accept that garbage. NW1 men aren't walking around with b**ch tits, libidoless and moody. A proper drug will only castrate your scalp and nothing else. Them's the breaks.

Yeah, thats what we actually want, but with the current things we have, we can't overcome the systemic absorption, sadly. Hope those local drugs will come out sooner or later.

 

[inmyhead]

Thanks for the post.
Why are you guys so excited? As far as I understand, this stuff would still have to go Phase 1, 2, 3.. which would take a while?

 

[Isneezedsohard]

Thanks for the post.
Why are you guys so excited? As far as I understand, this stuff would still have to go Phase 1, 2, 3.. which would take a while?

I think any new, safe, effective treatment is exciting