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Long-term treatment with finasteride 1 mg decreases the likelihood of developing further visible hair loss in men with androgenetic alopecia (male pattern hair loss)
Eur J Dermatol. 2008 Jun 23;18(4):400-406.
Kaufman KD, Rotonda J, Shah AK, Meehan AG.
Merck Research Laboratories, 126 East Lincoln Avenue, RY34-A248, Rahway, NJ 07065, USA.
There are no reports on the effects of pharmacologic treatment on the likelihood of developing further visible hair loss in men with androgenetic alopecia (Androgenetic Alopecia). Our objectives were to examine whether finasteride 1 mg treatment decreases the likelihood of developing further visible hair loss in men with Androgenetic Alopecia. We conducted an analysis of global photographic assessment data from two Phase III trials in which 1553 men with Androgenetic Alopecia received finasteride 1 mg/day or placebo for up to 5 years. Finasteride 1 mg treatment led to a 93% decrease relative to placebo in the 5-year likelihood of developing further visible hair loss (95% CI: 89-97%; p < 0.001). We conclude that, in men with Androgenetic Alopecia, treatment with finasteride 1 mg/day over 5 years led to a marked and sustained decrease in the likelihood of developing further visible hair loss.
PMID: 18573712
Eur J Dermatol. 2008 Jun 23;18(4):400-406.
Kaufman KD, Rotonda J, Shah AK, Meehan AG.
Merck Research Laboratories, 126 East Lincoln Avenue, RY34-A248, Rahway, NJ 07065, USA.
There are no reports on the effects of pharmacologic treatment on the likelihood of developing further visible hair loss in men with androgenetic alopecia (Androgenetic Alopecia). Our objectives were to examine whether finasteride 1 mg treatment decreases the likelihood of developing further visible hair loss in men with Androgenetic Alopecia. We conducted an analysis of global photographic assessment data from two Phase III trials in which 1553 men with Androgenetic Alopecia received finasteride 1 mg/day or placebo for up to 5 years. Finasteride 1 mg treatment led to a 93% decrease relative to placebo in the 5-year likelihood of developing further visible hair loss (95% CI: 89-97%; p < 0.001). We conclude that, in men with Androgenetic Alopecia, treatment with finasteride 1 mg/day over 5 years led to a marked and sustained decrease in the likelihood of developing further visible hair loss.
PMID: 18573712