2young posted an interesting paper (which i posted earlier), all he got was comments to derail this post. He did NOT write the paper, so his credibility has nothing to do with this.
i would like to see a discussion of the duplication, if correct, than pilofocus should be well able to regenerate and yes that would be extremely promising.... The scientists did not see a difference inhair quality but you know i d like to see more evidence...
let s discuss this not the previous life of 2young
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This is from 1998!
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Follicular bisection in hair transplantation surgery: an in vitro model.[/FONT][/h][FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]
Raposio E1, Filippi F, Levi G, Nordström RE, Santi P.[/FONT]
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[FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]Author information[/FONT][/h]
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Abstract[/FONT][/h][FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]The aim of this study was to evaluate, in an in vitro model, the survival and growth rates of transversely sectioned human hair follicles to assess experimentally the soundness of this approach as a future possible method for "duplicating" available donor hair grafts in hair transplantation procedures. A total of 300 human anagen hair follicles was obtained from 10 healthy male patients. Follicles were thus randomly assigned to one of the following groups: group A (control; n = 100 follicles), cultured intact as dissected, and group B (experimental; n = 200 follicles), transversely transected, parallel to the epidermal surface and immediately below the bulge area, to obtain 200 lower-half follicles and 200 upper-half follicles. Isolated hair follicles from both groups were maintained in culture for 10 days. The length of each follicle was measured immediately following isolation and at the end of the 10-day culture period. No statistically significant differences were found between the growth rate of intact follicles (mean 10-day growth rate = 2.71 mm) and of lower-half follicles (mean 10-day growth-rate = 2.64 mm), whereas a statistically significant difference was found between the growth rate of follicles from the two above-mentioned groups and the growth rate of the "upper-half" follicles (mean 10-day growth rate = 1.07 mm). Histologic analysis demonstrated that both intact and lower-half follicles maintained a normal histologic appearance, whereas in upper-half follicle sections we invariably detected a region of intense cell proliferation, reminiscent of a regenerated follicular papilla, surrounding the lowermost part of the follicle. In our opinion, the reported in vitro survival rate of transected human hair follicles might represent an interesting starting point in striving to augment the number of donor hairs available during a hair transplantation procedure.[/FONT]
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Both studies transect the follicle in upper and lower half (surprising i find).... The fact that this was not put into practice yet makes me a bit skeptic but definitely worth discussing...
i am much more amenable to be convinced of the regeration of trasected follicles than plucked hairs becoming follicles...
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This study is based on fue transected follicles, so not exactly the same as the two studies above, the rsults are not so good but there is regeneration
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BACKGROUND Follicular unit extraction is a process of removing one follicular unit at a time from the donor region. The most important limitation of this surgical procedure is a high transection rate.[/FONT]
[FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]OBJECTIVE In this clinical study, we have transplanted different parts of transected hair follicle by harvesting with the follicular unit extraction technique (FUE) in five male patients.[/FONT]
[FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]MATERIALS AND METHODS In each patient, three boxes of 1 cm[SUP]2[/SUP] are marked at both donor and recipient sites. The proximal one-third, one-half, and two-thirds of 15 hair follicles are extracted from each defined box and transplanted in recipient boxes. The density is determined at 12 months after the procedure.[/FONT]
[FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]RESULTS A mean of 3 (range, 2–4) of the proximal one-third, 4.4 (range, 2–6) of the proximal one-half, and 6.2 (range, 5–8) of the proximal two-thirds of the transplanted follicles were observed as fully grown after 1 year. At the donor site, the regrowth rate was a mean of 12.6 (range, 10–14) of the proximal one-third, 10.2 (range, 8–13) of the proximal one-half, and 8 (range, 7–12) of the proximal two-thirds, respectively.[/FONT]
[FONT=Verdana, Arial, Tahoma, Calibri, Geneva, sans-serif]CONCLUSION The survival rate of the transected hair follicles is directly related to the level of transection. Even the transected parts, however, can survive at the recipient site; the growth rate is not satisfactory and they are thinner than the original follicles. We therefore recommend that the surgeon not transplant the sectioned parts and be careful with the patients whose transection rate is high during FUE procedures.[/FONT]
