Hi everyone,
Here's my first post in this forum.
Well, as most of you, I noticed losing hair at some point and I somehow panicked. started to realising my head without hair and my bald shining scalp under sunny days of summer! Although, my father and my uncles are all bald and I had always imagined part of me staring at my eyes, pointing at my father's head telling me: "You'll be like that". but I was in somewhat ignorance!
Then I realized, "I can't cope with getting bald like this! I should do a maneuver toward losing hair!". So I started to reorganize thoughts and designing a maneuver. To do so I did research, read so much academic articles in pubmed, forums and people's review.
Finally I decided to start from:
1) The Psychology
You should at some point accept the fact that you'll be eventually bald. Maybe they find a solution to it in a near future or you may read/hear about another drug/lotion, but it is not a disease! Losing hair is and always has been a part of Human Evolution, didn't you forget?
I can imagine how embarrassed was the chimpanzee who lost his facial hair in front of tribe's ladies! And bear in mind, not accepting this fact won't stop you from losing hair, yet stress and anxiety from it will actually cause losing more hair.
Try to realize 70-80 percent of men are same as you, successful people who have the same problem, some of them have even shaved the remainings, like many Hollywood actors. If you're concerning your looks, having hair isn't the only factor of being handsome. I did work on my body and facial muscles for 3 months during hair treatments then noticed getting more looks from women, specially mid-age ladies, hehehe!
One night I had a dream about combing my hair in front of a mirror so serious that comb did break!! you may had similar dreams, because we all are doing things to our unconscious part of our mind in our lifetime. And if you lose your unconscious health, you'd lose your life's happiness.
If you try to think about it this night, about how you are managing losing hair in your mind, you'd finally understand stresses and sadness from losing hair are having much more impact on your health than the hair falling out itself!
2) The Cause
After so much research and reading various articles and trials, I understood the end of line cause of hair thinning and falling out is malnutrition of the Hair Follicle. But what causes the malnutrition your ask? it is somehow caused by Follicle Inflammation, which is caused by elevated COX-Enzyme which is because of Histamine Release. And who releases Histamine? Mast Cell (or mastocyte) does, which is triggered by DHT (Dihydrotestosterone). And DHT is being assembled by 5a-reductase Enzyme with Testosterone.
Actually Mast Cells are part of body's Immune System, But why its being triggered by DHT at some age is still unknown! Some believe its related to Genetics, Some say it is an Allergic Reaction and some are researching on Immune Disorders which may cause this.
However, In our maneuver what is important to us is Malnutrition, Histamine and DHT. Hair have a cycle of 3 steps:
1- Anagen Phase: Growth or regrowth of hair in follicle after Telogen Phase.
2- Catagen Phase: Resting/Recovery of follicle, or known as Transitional phase. New hair won't grow in this phase.
3- Telogen Phase: During this phase (which is 3 to 4 months) hair grow in length and follicle will uses its nutrition to do so, then growth will be reversed and hair gets thin to finally falls out. Then follicle will go to Anagen Phase again.
Malnutrition will cause the Hair Follicle to remain in Catagen and Telogen phase too long which eventually hair gets thin and falls out and because of the same problem, Hair Follicle won't cycle through Anagen Phase and new hair wouldn't grow. After 1 to 2 months follicle will die of malnutrition.
3) The Treatment
You may think of taking oral or topical Vitamins and Minerals, But it won't help your Hair Follicles as long as it being inflamed. Also, your blood serum already have the needed amount of those nutrients in the first place. So, you have to:
1. Take Oral DHT inhibitors: To decrease the conversion of Testosterone to DHT by blocking 5a-reductase Enzyme. There are 3 kinds of this enzyme, which Finasteride 1mg/daily (Best would be around 20:00 to 22:00, Because high level of DHT serum is in night-time) blocks 2 kinds of them, which is pretty enough! I have seen a lot of people taking Dutasteride which blocks all three. Yes! that'd be significant in case of fighting hair loss. But bear in mind, You'd damage your prostate so it will get large then you'd experience more frequently urinating and at the end Cancer comes... maybe not now or even near future, but when you age it will.
2. Blocking DHT (Androgen) Receptors in Hair Follicle and Mastocytes: This will relieve your Hair Follicles from inflammation and you should do it topically. We don't want to block all of our Androgenic Receptors through out of our body! To do so, you need to get Fluridil or if you don't have access to it (Like me) you can use Ketoconazole Shampoo 2% daily before going to bed.
3. Fighting Inflammation: Hair Follicle Inflammation is the main cause of not getting enough nutrients. Inflammation is caused by Histamine Release and elevated levels of COX-enzyme, Ketoconazole Shampoo 2% 3-times/week is effective in reducing inflammation. If you chose to use it daily its OK.
4. Promoting regrowth and nutritions: This step consists of 2 parts itself, which first one is optional:
4.1- PRP (Platelet Rich Plasma) Injection: This is a process of drawing blood, Centrifuge to separate Blood Cells and Plasma and Injection of Plasma to balding areas of scalp. Plasma is enriched with nutrients and growth factors like insulin-like hormones and B vitamins, Zinc and other minerals. PRP Injection would promote Hair regrowth and building new Blood Capillaries, so blood (read nutrients) circulation will be higher, Another benefit would be calming Mastocytes' Androgenic Receptors due to Insulin-Like Hormones, like IGF-1. I did PRP Injection once but anyone can do it every 6-months.
4.2- Topical Solution: I live in Iran and most of high-quality topicals won't get here. Not because of sanctions, but lack of knowledge! So, I decided to cook my own Topical, which you can too! if you have access to Equisomin, you don't need to!
Here is the recipe:
what you need are Melatonin 3mg Tablet, Caffeine 50mg Tablet, Zinc PCA, Panthenol (Vitamin B5), Niacinamide (Vitamin B3), Ethanol.
Most chemicals won't go through skin by itself, Because of this a vehicle (Skin Activator) will be needed. Ethanol would do the trick, but I preferred to use Alpecin C1 Liquid, which contains Caffeine, Zinc, B5, B3 and special (and patented) vehicle! If you too used Alpecin you only have to buy Melatonin 3mg Tablet and Ethanol for dissolution. Melatonin is a strong anti-oxidant and Hair Growth Promoter, it also calms Mastocytes and defuses Histamine release. Tablets have fillers, to get rid of them you have to heat your Ethanol + dissolved tablet solution a little bit. Then add your solution to Alpecin after filtering. I used napkin as filter!
Use the prepared solution as scalp topical every evening and (optional) in morning.
I have experienced a great result from this maneuver, I hope everyone of you experience the same. After a month you'd notice new tiny hairs which are getting darker and after 4 to 6 months your improvement will be easily noticeable.
Good luck,
M
Here's my first post in this forum.
Well, as most of you, I noticed losing hair at some point and I somehow panicked. started to realising my head without hair and my bald shining scalp under sunny days of summer! Although, my father and my uncles are all bald and I had always imagined part of me staring at my eyes, pointing at my father's head telling me: "You'll be like that". but I was in somewhat ignorance!
Then I realized, "I can't cope with getting bald like this! I should do a maneuver toward losing hair!". So I started to reorganize thoughts and designing a maneuver. To do so I did research, read so much academic articles in pubmed, forums and people's review.
Finally I decided to start from:
1) The Psychology
You should at some point accept the fact that you'll be eventually bald. Maybe they find a solution to it in a near future or you may read/hear about another drug/lotion, but it is not a disease! Losing hair is and always has been a part of Human Evolution, didn't you forget?
I can imagine how embarrassed was the chimpanzee who lost his facial hair in front of tribe's ladies! And bear in mind, not accepting this fact won't stop you from losing hair, yet stress and anxiety from it will actually cause losing more hair.
Try to realize 70-80 percent of men are same as you, successful people who have the same problem, some of them have even shaved the remainings, like many Hollywood actors. If you're concerning your looks, having hair isn't the only factor of being handsome. I did work on my body and facial muscles for 3 months during hair treatments then noticed getting more looks from women, specially mid-age ladies, hehehe!
One night I had a dream about combing my hair in front of a mirror so serious that comb did break!! you may had similar dreams, because we all are doing things to our unconscious part of our mind in our lifetime. And if you lose your unconscious health, you'd lose your life's happiness.
If you try to think about it this night, about how you are managing losing hair in your mind, you'd finally understand stresses and sadness from losing hair are having much more impact on your health than the hair falling out itself!
2) The Cause
After so much research and reading various articles and trials, I understood the end of line cause of hair thinning and falling out is malnutrition of the Hair Follicle. But what causes the malnutrition your ask? it is somehow caused by Follicle Inflammation, which is caused by elevated COX-Enzyme which is because of Histamine Release. And who releases Histamine? Mast Cell (or mastocyte) does, which is triggered by DHT (Dihydrotestosterone). And DHT is being assembled by 5a-reductase Enzyme with Testosterone.
Actually Mast Cells are part of body's Immune System, But why its being triggered by DHT at some age is still unknown! Some believe its related to Genetics, Some say it is an Allergic Reaction and some are researching on Immune Disorders which may cause this.
However, In our maneuver what is important to us is Malnutrition, Histamine and DHT. Hair have a cycle of 3 steps:
1- Anagen Phase: Growth or regrowth of hair in follicle after Telogen Phase.
2- Catagen Phase: Resting/Recovery of follicle, or known as Transitional phase. New hair won't grow in this phase.
3- Telogen Phase: During this phase (which is 3 to 4 months) hair grow in length and follicle will uses its nutrition to do so, then growth will be reversed and hair gets thin to finally falls out. Then follicle will go to Anagen Phase again.
Malnutrition will cause the Hair Follicle to remain in Catagen and Telogen phase too long which eventually hair gets thin and falls out and because of the same problem, Hair Follicle won't cycle through Anagen Phase and new hair wouldn't grow. After 1 to 2 months follicle will die of malnutrition.
3) The Treatment
You may think of taking oral or topical Vitamins and Minerals, But it won't help your Hair Follicles as long as it being inflamed. Also, your blood serum already have the needed amount of those nutrients in the first place. So, you have to:
1. Take Oral DHT inhibitors: To decrease the conversion of Testosterone to DHT by blocking 5a-reductase Enzyme. There are 3 kinds of this enzyme, which Finasteride 1mg/daily (Best would be around 20:00 to 22:00, Because high level of DHT serum is in night-time) blocks 2 kinds of them, which is pretty enough! I have seen a lot of people taking Dutasteride which blocks all three. Yes! that'd be significant in case of fighting hair loss. But bear in mind, You'd damage your prostate so it will get large then you'd experience more frequently urinating and at the end Cancer comes... maybe not now or even near future, but when you age it will.
2. Blocking DHT (Androgen) Receptors in Hair Follicle and Mastocytes: This will relieve your Hair Follicles from inflammation and you should do it topically. We don't want to block all of our Androgenic Receptors through out of our body! To do so, you need to get Fluridil or if you don't have access to it (Like me) you can use Ketoconazole Shampoo 2% daily before going to bed.
3. Fighting Inflammation: Hair Follicle Inflammation is the main cause of not getting enough nutrients. Inflammation is caused by Histamine Release and elevated levels of COX-enzyme, Ketoconazole Shampoo 2% 3-times/week is effective in reducing inflammation. If you chose to use it daily its OK.
4. Promoting regrowth and nutritions: This step consists of 2 parts itself, which first one is optional:
4.1- PRP (Platelet Rich Plasma) Injection: This is a process of drawing blood, Centrifuge to separate Blood Cells and Plasma and Injection of Plasma to balding areas of scalp. Plasma is enriched with nutrients and growth factors like insulin-like hormones and B vitamins, Zinc and other minerals. PRP Injection would promote Hair regrowth and building new Blood Capillaries, so blood (read nutrients) circulation will be higher, Another benefit would be calming Mastocytes' Androgenic Receptors due to Insulin-Like Hormones, like IGF-1. I did PRP Injection once but anyone can do it every 6-months.
4.2- Topical Solution: I live in Iran and most of high-quality topicals won't get here. Not because of sanctions, but lack of knowledge! So, I decided to cook my own Topical, which you can too! if you have access to Equisomin, you don't need to!
Here is the recipe:
what you need are Melatonin 3mg Tablet, Caffeine 50mg Tablet, Zinc PCA, Panthenol (Vitamin B5), Niacinamide (Vitamin B3), Ethanol.
Most chemicals won't go through skin by itself, Because of this a vehicle (Skin Activator) will be needed. Ethanol would do the trick, but I preferred to use Alpecin C1 Liquid, which contains Caffeine, Zinc, B5, B3 and special (and patented) vehicle! If you too used Alpecin you only have to buy Melatonin 3mg Tablet and Ethanol for dissolution. Melatonin is a strong anti-oxidant and Hair Growth Promoter, it also calms Mastocytes and defuses Histamine release. Tablets have fillers, to get rid of them you have to heat your Ethanol + dissolved tablet solution a little bit. Then add your solution to Alpecin after filtering. I used napkin as filter!
Use the prepared solution as scalp topical every evening and (optional) in morning.
I have experienced a great result from this maneuver, I hope everyone of you experience the same. After a month you'd notice new tiny hairs which are getting darker and after 4 to 6 months your improvement will be easily noticeable.
Good luck,
M
