N-acetyl-cysteine For Treatment Of Androgenetic Alopecia In Men

[jamesbooker1975]

Pretty interesting since they will compare with minoxidil :
https://clinicaltrials.gov/ct2/show/NCT04209803?term=androgenetic+alopecia&recrs=a&draw=2&rank=4

 

[Xander94]

results ?

 

[Derelict]

I have been taking it for about 4 weeks or so for things unrelated to hair loss, so i can't say i have noticed any results hair wise, but i'll keep people updated just in case. Im only taking 200mg though, they used 600mg in the study.

 

[inmyhead]

results ?

Its currently recruiting...
Estimated Study Completion Date ICMJE October 2020
The second group will receive NAC orally 600 mg 3 times a day for 4 months.

 

[arnoldd]

Through which mechanism NAC help with hair loss ?

 

[Xander94]

Through which mechanism NAC help with hair loss ?

Google it there are many studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133876/
ROS induced TGF-β1 secretion in the DPCs, and that NAC inhibits androgen-induced TGF-β1 secretion at the transcriptional level

 

[nick123]

What interests me is this study is a Phase 4 study? Where are the results for the previous phases..

 

[inmyhead]

What interests me is this study is a Phase 4 study? Where are the results for the previous phases..

Maybe it's because cysteine is already verified as a safe supplement?

Wonder what this study si based on..

This one
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017824/#B16-molecules-23-00575
mentions possitive effect on hair growth and cites https://www.ncbi.nlm.nih.gov/pubmed/27095961

Also this,
https://www.ncbi.nlm.nih.gov/pubmed/19581567

 

[MrJolly26]

There are many products we are going to wait for, but will they work? :S

 

[inmyhead]

There are many products we are going to wait for, but will they work? :S

?? What.. You can buy this anywhere. The question is if this is efficient. Taurine has more proof probably.

 

[jamesbooker1975]

?? What.. You can buy this anywhere. The question is if this is efficient. Taurine has more proof probably.

Correct, Wonder why people answer without even care on what they are answer and use generic answers.

 

[shulk]

took its 3 times daily at 600mg for 2 months as biofilm disruptor. Did nothing for my hair loss as far as i know, was not even aware it "could" do something.

 

[whatevr]

The ROS / TGF-beta angle doesn't seem to be a major one. None of the things on that pathway that I've used (Tempol, NAC/glutathione, Taurine, T-flavanone) have even slowed down my hair loss.

You'd probably have more success putting liposomal vitamin C (magnesium ascorbyl phosphate) on your head - DKK1 seems to be a bigger player than TGF-beta.

 

[furtbr]

That's crazy, man. I just started yesterday this treatment by myself.

 

[el_duterino]

NAC has been flagged as a lung carcinogen

Maybe not somthing you want to take for a long time

https://insight.jci.org/articles/view/127647

 

[jamesbooker1975]

NAC has been flagged as a lung carcinogen

Maybe not somthing you want to take for a long time

https://insight.jci.org/articles/view/127647

If you were a MICE.

 

[el_duterino]

If you were a MICE.

Not really, the mouse model has been used for decades of studying lung cancer as it correlates well to human lung cancer. The 5-year survival rate for men with lung cancer is 16% not something you want to risk, at least for hair.

 

[furtbr]

Not really, the mouse model has been used for decades of studying lung cancer as it correlates well to human lung cancer. The 5-year survival rate for men with lung cancer is 16% not something you want to risk, at least for hair.

You need to see the dosage. Even water kills a person given the amount. They were probably stuffing the mice with the substance.

 

[whatevr]

Not really, the mouse model has been used for decades of studying lung cancer as it correlates well to human lung cancer. The 5-year survival rate for men with lung cancer is 16% not something you want to risk, at least for hair.

Believes NAC will cause lung cancer.

Uses RU58841 daily for years believing its safe.

Alright.

 

[Seuxin]

NAC has been flagged as a lung carcinogen

Maybe not somthing you want to take for a long time

https://insight.jci.org/articles/view/127647

What is this shitty studies ? NAC is used to protect from Cancer too...Too much paranoids...