Need To Modulate minoxidil Transdermal Absorption! Help!

mig89

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Hello, I am from Argentina. Ive been using minoxidil for quite a while, about 10 years, on and off. One year ago i quit and i experienced a lot of changes in my mood, libido, anxiety levels, weight (all for positive). On the bad side, my hair lost density (gone from Norwood 1,5 to nw2, diffuse thining). I tried minoxidil again in a low dose, and some sides came back but a little (i was using 2 times a week 0,5ML). Now ive decided to use 0,5ml a day, and i got ALL the sides, the principal are increase in anxiety, liquid retention, shortness of breath, loss of morning erections and the libido i think it is because im more anxious, all in ONE WEEK!. The thing is i think i have an increased permeability in my scalp, or something like that. 15 min after aplying 0,4 ML of minoxidil i have a lot of tachychardia and palpitations! I couldnt event think of aplying 1 ml, or 2! I need to ask people with knowledge about minoxidil formulation! I was looking for a formulation that doesnt favor absorption! The actual minoxidil i Use has 50% ethyl alcohol and 20g of propilenglicol! Do someone know the proportions to reduce transdermal absorption? Thank you very much!
 

Roberto_72

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15 min after aplying 0,4 ML of minoxidil

What minoxidil percentage? 2% or 5%?
Basically you have
- sexual side effects
- heart side effects
- neurological side effects
Don't you think that if so little minoxidil (0.4ml) does that effect to you, then you should not use it?

There are topical alternatives: aminexil (with a very similar molecule to minoxidil), stemoxydine.
 

cyrusthegreat@hotmail.com

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You can try switching to 2% if using 5%. Beyond that, you can try formulations that use glycerin instead of propylene glycol - that will reduce the scalp permeability. For instance, you can liquifying rogaine foam and apply like the solution.
 

mig89

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What minoxidil percentage? 2% or 5%?
Basically you have
- sexual side effects
- heart side effects
- neurological side effects
Don't you think that if so little minoxidil (0.4ml) does that effect to you, then you should not use it?

There are topical alternatives: aminexil (with a very similar molecule to minoxidil), stemoxydine.
Yes Its a harsh to use it, but you know how this is , i want to conserve my hair jaja. The problem is that here in my country none of that products arrive, but ill investigate about, maybe i can get them!. I use 5% minoxidil
 

mig89

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You can try switching to 2% if using 5%. Beyond that, you can try formulations that use glycerin instead of propylene glycol - that will reduce the scalp permeability. For instance, you can liquifying rogaine foam and apply like the solution.
So If I use a solution with LESS PPG and MORE alcohol the absorption will be limited??? What would happen if I add Glycerin to the half of my minoxidil bottle? thanks!
 

Roberto_72

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cyrusthegreat@hotmail.com

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So If I use a solution with LESS PPG and MORE alcohol the absorption will be limited??? What would happen if I add Glycerin to the half of my minoxidil bottle? thanks!

Don't start mixing your own minoxidil solutions, you're over complicating it. Just look online for minoxidil products that include glycerin instead of ppg - they are made for people with PPG sensitivity or allergy.
 
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