New Study: Effect Of A Sphingolipid-mimetic Compound On The Promotion Of Hair Growth:

HairtotheDome

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Effect of a sphingolipid-mimetic compound on the promotion of hair growth: A randomized, double-blind, placebo-controlled clinical trial.

Abstract
BACKGROUND:
Pattern hair loss is a very common skin disorder, but more therapeutic modalities for hair growth are still required.

OBJECTIVE:
We investigated the effect of a newly synthesized sphingolipid-mimetic compound (pseudo-ceramide: bis-oleamide isopropyl alcohol [BOI]) on the promotion of hair growth for patients with mild pattern hair loss.

METHODS:
A total of 58 patients with mild pattern hair loss participated in this clinical trial. A randomized, double-blind, placebo-controlled clinical trial was conducted for 6 months. Participants in the experimental group applied 1% BOI lotion (ceramide HS) on the whole scalp once a day for 6 months. Participants in the control group applied simulacrum using the same protocol. We evaluated daily hair loss, hair density, hair thickness, and hair length at intervals of 3 months; patient satisfaction and adverse events were evaluated at 6 months.

RESULTS:
At 6 months in the experimental group, daily hair loss at baseline (52.52 ± 33.98) decreased to 40.41 ± 24.78, vertex hair density at baseline (131.07 ± 43.73) increased to 156.00 ± 39.59, frontal hair density at baseline (104.21 ± 30.72) increased to 124.10 ± 28.28, thickness of vertex hair at baseline (0.067 ± 0.012 cm) increased to 0.075 ± 0.014 cm, thickness of frontal hair at baseline (0.070 ± 0.009 cm) increased to 0.076 ± 0.012 cm, and hair growth rate was 16.17 ± 1.89 mm/month.

CONCLUSION:
Ceramide HS may be a new candidate for the treatment of pattern hair loss.

 

badhabiz

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very interesting, another study that confirms Wnt/β-catenin pathway efficacy. I assume it is already on its way to be on the market with follica (same pathway, another angle).
but this way seems to be good
 

NotInmywatch

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full article attached
 

Attachments

  • 10.1111@jocd.13220.pdf
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tomJ

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very interesting, another study that confirms Wnt/β-catenin pathway efficacy. I assume it is already on its way to be on the market with follica (same pathway, another angle).
but this way seems to be good
Dont assume anything. It will be shelved like the hundreds of other studies that we read about that had positive outcomes. I'm a realist.
 

badhabiz

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Dont assume anything. It will be shelved like the hundreds of other studies that we read about that had positive outcomes. I'm a realist.
i really dont know, im just waiting here like you. was thinking that i appreciate the fact the the hormonal route seems to be dismissed for future treatments, thats all
 

Trauma

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Dont assume anything. It will be shelved like the hundreds of other studies that we read about that had positive outcomes. I'm a realist.

It angers me so much because it's true. It always happens. Hopefully not this time with how much competition to bring out efficient solutions to our problem is out there.
 

tomJ

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It's all a tease. Kind of like the cute rinder girl that showed interest but then you never heard from her again. Vanish like a fart in the wind.
 

Trauma

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It's all a tease. Kind of like the cute rinder girl that showed interest but then you never heard from her again. Vanish like a fart in the wind.

Even when I was still full thick NW1 about 4-5 years ago in my mid twenties they were doing that, lol. I had like 380 matches by the time I quit after about a full year or two of tinder, and I probably met with like 15 of them at most. About 4 lasted more than a one nighter.
 
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