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11/27/2015
I'm starting this posting on the 11th month mark for Minoxidil. I never really thought about being an active/contributing member to any forum but seeing how much research and effort members are putting into this I thought why not... I look good bald but I don't like shaving my head every day, which I did until I cut about a dime sized sliver of skin off - that sucked. Not my first shaving accident but the worse to date.
I started with minoxidil then started making stuff in my kitchen.
Essential oils, caffeine, scalp massage, copper based salicylates, vitamin enriched topicals.
I probably did more to stunt my progress than to help but it was actually kind of fun in a way (I need more of a life)
What surprised me the most when I did decide to do something was the lack of options - the big 3 or self-mutilation (Hair transplant). Minoxidil before and after pictures didn’t really exist in isolation of other treatments. I usually ran across the same 3 or 4 guys doing YouTube videos or hair transplant photo when all I wanted to know was what to expect on minoxidil only. I guess not much happens at this level of hair loss but I did catch a bad case of the velluses.
I’m currently cooking up another overly complicated mixture that might make my hair fall out but I decided to let it all hang out in public just in case I do have some success. Hey, I’m already bald so a little less hair won’t hurt
Age: 41
Norwood Grade: 5a
Short-term goal: 5
Long-term goal: Full restoration
The new concoction is going to be a RU/TM mixture along with B-UVB exposure
No uvb burns for me. I’m doing the vitiligo method of short exposures a few times a week. I’m trying to activity my Vitamin D receptors, increase pge2, and decrease pgd2 to initiate a growth cycle not to damage myself.
Warning - Mouse study’s ahead
“Cutaneous exposure to UVB irradiation is an important source of vitamin D. Here, we examined sex-specific differences in cutaneous vitamin D production in mice. Both male and female mice on a vitamin D–deficient diet manifested vitamin D deficiency, with mineral abnormalities, secondary hyperparathyroidism, and osteomalacia. UVB irradiation significantly increased vitamin D levels in the skin of female mice and normalized serum 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 levels, as well as mineral and skeletal abnormalities. However, in male mice, the vitamin D response to UVB was attenuated and mineral and skeletal abnormalities were not normalized. The vitamin D precursor, 7-dehydrocholesterol (7DHC), was significantly lower in the skin of male than female mice. This reduction was due to local androgen action in the skin as demonstrated by castration studies and skin-specific androgen receptor deletion in male mice, both of which reversed the male phenotype. Local androgen regulation in the skin of the CYP11A1 gene, which encodes a crucial enzyme that metabolizes cholesterol, 7DHC, and vitamin D, appeared to contribute to the gender differences in UVB-induced vitamin D production and to its reversal of vitamin D deficiency. Sex-specific, enzymatically regulated differences in cutaneous production of vitamin D may therefore be of importance to ensure vitamin D sufficiency.”
http://www.nature.com/jid/journal/v1...d2015297a.html
The above study was the main reason I decided to add an anti-androgen component to my uvb treatment. A few years past, there were news reports that vitamin D might hold the cure to hair loss and many people started adding vitamin D to their diets with the hope that hair would miraculously reappear but it proved to be a bust. I think that topical, along with internal vitamin d had no effect because the vitamin d receptors (vdr) were inactive due to androgens.
There was a study of a 73-year-old man who grow some of his hair back on spironolactone suddenly even though he’s been taking it for 6 years prior. This is speculation but I wouldn’t be surprised if he had gotten a sunburn on his reduced androgen scalp sometime during the year.
http://www.ncbi.nlm.nih.gov/pubmed/1977262
Concerning UVB
UVB has been identified as a possible cause of cancer
It raises pge2 and lowers pgd2
It activities vitamin d receptors
UVB induces hedgehog activation
It has a 50-year history of controlling skin issues but please do your own research
My main hope for this upcoming uvb test is to see if I can activate my dormant vdr, raise my pge2 and lower my pgd2. Simple right? Bro science at its finest!!!!
I haven’t started yet because I’m still waiting on my TM to arrive. I’m making a cream because I’m bald enough that it won’t mess up my hair and I need it to stay on my scalp without running off.
So I’m rolling the dice on converting more vellus to terminal
Note: There is no delusion about a full recovery but I do enjoy the challenge
1/2/2016
One month is not indicative of any treatment but I knowing used a weaker concentration of my intended mixture because RU and TM is a little too expensive for my taste. (1% of RU and .125% of TM) I'm also using this in conjunction with a vitamin enriched massage oil that failed due to insolubility/oxidation issues and the new batch didn’t quite work out either but it’s a little better than prior month.
Results NULL but like I said one month is not indicative of any treatment
11/27/2015
Everything in red was squeaky clean
1/2/2016
Null results - some peeling due to new massage oil - On to month 2
I'm starting this posting on the 11th month mark for Minoxidil. I never really thought about being an active/contributing member to any forum but seeing how much research and effort members are putting into this I thought why not... I look good bald but I don't like shaving my head every day, which I did until I cut about a dime sized sliver of skin off - that sucked. Not my first shaving accident but the worse to date.
I started with minoxidil then started making stuff in my kitchen.
Essential oils, caffeine, scalp massage, copper based salicylates, vitamin enriched topicals.
I probably did more to stunt my progress than to help but it was actually kind of fun in a way (I need more of a life)
What surprised me the most when I did decide to do something was the lack of options - the big 3 or self-mutilation (Hair transplant). Minoxidil before and after pictures didn’t really exist in isolation of other treatments. I usually ran across the same 3 or 4 guys doing YouTube videos or hair transplant photo when all I wanted to know was what to expect on minoxidil only. I guess not much happens at this level of hair loss but I did catch a bad case of the velluses.
I’m currently cooking up another overly complicated mixture that might make my hair fall out but I decided to let it all hang out in public just in case I do have some success. Hey, I’m already bald so a little less hair won’t hurt
Age: 41
Norwood Grade: 5a
Short-term goal: 5
Long-term goal: Full restoration
The new concoction is going to be a RU/TM mixture along with B-UVB exposure
No uvb burns for me. I’m doing the vitiligo method of short exposures a few times a week. I’m trying to activity my Vitamin D receptors, increase pge2, and decrease pgd2 to initiate a growth cycle not to damage myself.
Warning - Mouse study’s ahead
“Cutaneous exposure to UVB irradiation is an important source of vitamin D. Here, we examined sex-specific differences in cutaneous vitamin D production in mice. Both male and female mice on a vitamin D–deficient diet manifested vitamin D deficiency, with mineral abnormalities, secondary hyperparathyroidism, and osteomalacia. UVB irradiation significantly increased vitamin D levels in the skin of female mice and normalized serum 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 levels, as well as mineral and skeletal abnormalities. However, in male mice, the vitamin D response to UVB was attenuated and mineral and skeletal abnormalities were not normalized. The vitamin D precursor, 7-dehydrocholesterol (7DHC), was significantly lower in the skin of male than female mice. This reduction was due to local androgen action in the skin as demonstrated by castration studies and skin-specific androgen receptor deletion in male mice, both of which reversed the male phenotype. Local androgen regulation in the skin of the CYP11A1 gene, which encodes a crucial enzyme that metabolizes cholesterol, 7DHC, and vitamin D, appeared to contribute to the gender differences in UVB-induced vitamin D production and to its reversal of vitamin D deficiency. Sex-specific, enzymatically regulated differences in cutaneous production of vitamin D may therefore be of importance to ensure vitamin D sufficiency.”
http://www.nature.com/jid/journal/v1...d2015297a.html
The above study was the main reason I decided to add an anti-androgen component to my uvb treatment. A few years past, there were news reports that vitamin D might hold the cure to hair loss and many people started adding vitamin D to their diets with the hope that hair would miraculously reappear but it proved to be a bust. I think that topical, along with internal vitamin d had no effect because the vitamin d receptors (vdr) were inactive due to androgens.
There was a study of a 73-year-old man who grow some of his hair back on spironolactone suddenly even though he’s been taking it for 6 years prior. This is speculation but I wouldn’t be surprised if he had gotten a sunburn on his reduced androgen scalp sometime during the year.
http://www.ncbi.nlm.nih.gov/pubmed/1977262
Concerning UVB
UVB has been identified as a possible cause of cancer
It raises pge2 and lowers pgd2
It activities vitamin d receptors
UVB induces hedgehog activation
It has a 50-year history of controlling skin issues but please do your own research
My main hope for this upcoming uvb test is to see if I can activate my dormant vdr, raise my pge2 and lower my pgd2. Simple right? Bro science at its finest!!!!
I haven’t started yet because I’m still waiting on my TM to arrive. I’m making a cream because I’m bald enough that it won’t mess up my hair and I need it to stay on my scalp without running off.
So I’m rolling the dice on converting more vellus to terminal
Note: There is no delusion about a full recovery but I do enjoy the challenge
1/2/2016
One month is not indicative of any treatment but I knowing used a weaker concentration of my intended mixture because RU and TM is a little too expensive for my taste. (1% of RU and .125% of TM) I'm also using this in conjunction with a vitamin enriched massage oil that failed due to insolubility/oxidation issues and the new batch didn’t quite work out either but it’s a little better than prior month.
Results NULL but like I said one month is not indicative of any treatment
11/27/2015
Everything in red was squeaky clean
1/2/2016
Null results - some peeling due to new massage oil - On to month 2
