2% Nizoral is not necessary for the majority of hair loss sufferers. It is prescription strength. People tend to overdo treatments in response to the psychological stress of losing hair, and the fear of further loss. This leads them to assume that if 1% is good, 2% must be better. The fact is, 2% is not necessary if you have no itch or typical itching and tingling. The 1% will take care of it just fine. The 2% is for men with severe scalp conditions tied to inflammation, which Im willing to bet even Ali does not have. 2% has been said to have growth stimulating properties, but ketokonazole also puts a strain on your liver, and there's no reason to use more of it unnecessarily.
To my knowledge there is no such thing as a Nizoral shed. And if there is, it would be subject to the same response times as any other shed.
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