Oral minoxidil Sides? Are They That Bad? Is It Worth It?

UnknownT

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Been prescribed oral minoxidil by my dermo but reading a lot of negative comments about the possible sides.. collagen destruction, bad skin, puffy eyes etc.

Anyone had any experience with any sides on oral minoxidil? Or any great success?
 

Derelict

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Just water retention, no problems with collagen or heart, blood pressure etc at 10mg.
 

UnknownT

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Yeah i take 10mg, was taking as high as 20mg, but reduced it. If 2.5mg is helping for you then no need to increase it and increase the risk of possible sides.

Yeah wow even 10mg sounds really high.

Im only 4 weeks so still v early.

Whats your regrowth been like? U get much all over ur body?
 

Ziggyz123

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I take 2.5 twice a day. Started October 1st so exactly one month ago. I had flushing sides where my ears got hot and red, but that may be from foods I eat. other than that, sometimes I get slight heart palpitations at random. I’m not really expecting a miracle at this dosage Or bad sides.

when I used minoxidil topically years and years ago, my facial hair benefitted greatly from it instantly which isn’t happening with oral. Time will tell. Going to give it 6 months and then that’s that. Tried everything else besides going female and that’s NOT happening
 

Derelict

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I take 2.5 twice a day. Started October 1st so exactly one month ago. I had flushing sides where my ears got hot and red, but that may be from foods I eat. other than that, sometimes I get slight heart palpitations at random. I’m not really expecting a miracle at this dosage Or bad sides.

when I used minoxidil topically years and years ago, my facial hair benefitted greatly from it instantly which isn’t happening with oral. Time will tell. Going to give it 6 months and then that’s that. Tried everything else besides going female and that’s NOT happening

What have you tried so far to stop hair loss?
 

Ziggyz123

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Everything dude.. spironolactone, cypro, seti, finasteride, dutasteride, prp, kenalog injections, doxycycline, itraconazole, topical anti fungals, keto shampoo, sulfasalazine, etc..

My hair line hasn’t stopped receding and tingling/itching in like 6 years now regardless of what I take. Now I’m only on oral min at 5mg a day and dutasteride at 2.5 every third day.

What have you tried so far to stop hair loss?
 

Shad264

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Well I have been taking 5 mg for a few months now , ya I feel they have been pretty effective on my frontal areas specially
But if u have a heart condition then i would definitely say no
And yes it's not a miracle or something.
 

StevenGerrard

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Well I have been taking 5 mg for a few months now , ya I feel they have been pretty effective on my frontal areas specially
But if u have a heart condition then i would definitely say no
And yes it's not a miracle or something.

even at a low dosage? 2.5mg/nightly?

I'm pretty sure I'm on everything (minus "tranny drugs" and minoxidil liquid or oral)

growing impatient over here :(
 

pegasus2

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even at a low dosage? 2.5mg/nightly?

I'm pretty sure I'm on everything (minus "tranny drugs" and minoxidil liquid or oral)

growing impatient over here :(

You might ask your doctor about adenosine. It might be safer for you. That is what they use in Japan instead of minoxidil. It has similar efficacy, and it's believed minoxidl may actually work, in part, through adenosine receptors in the DP. Another growth stimulator that doesn't affect the heart is redensyl. Stemoxydine is another one.

https://www.semanticscholar.org/pap...ashi/ea7c6a5efc4247e90ba9521acd6cd3a011e53200

Looking at your regimen you really don't need to be on dutasteride and finasteride. Dutasteride .5mg reduces your serum DHT by over 90%. Adding finasteride to that isn't going to do anything else.

You can try taurine supplements and copper peptides to reverse fibrosis. Folic acid and MSM are good for hair. Some more expensive supplements that might help are resveratrol, nicotamide riboside, and glisodin.

A lot of people are using CB-03-01 now which is very effective at first. I'm wary of that and other AR blockers because of the trial data showing CB's effectiveness dropping off a cliff between months 6 and 12. That has me concerned that it increases AR sensitivity thus making the situation worse in the long run.

There is also the prostglandin approach to try. PGE2 is expensive, but it should work for you, along with prostglandin analogues bimataprost and latanoprost. Blocking PGD2 with setipiprant is popular, but seti is a rather weak PGD2 inhibitor. Ramatroban is much stronger, and TM30089 virtually eliminates it. I noticed a marked decrease in shedding when I tried ramatroban.

There's the WNT agonists, SM04554 and WAY-316606. SM was moderately effective in phase 2 trials. WAY only has a six day trial, but should be more potent. I'll be adding it to my regimen next week. A few others have reported success with it. If I have any I'll report it on here.

You have lots of options besides minoxidil. There are many more.
 

Upnadam10

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I take 2.5 twice a day. Started October 1st so exactly one month ago. I had flushing sides where my ears got hot and red, but that may be from foods I eat. other than that, sometimes I get slight heart palpitations at random. I’m not really expecting a miracle at this dosage Or bad sides.

when I used minoxidil topically years and years ago, my facial hair benefitted greatly from it instantly which isn’t happening with oral. Time will tell. Going to give it 6 months and then that’s that. Tried everything else besides going female and that’s NOT happening
Ziggy - you're about at the 3 month. mark. How's it going?
 
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