PCT/US2013/036790 15-PGDH inhibitor

[Mach]

SOB! I deleted my earlier post.

Mentions hair 30 times and our new friend SW033291

http://www.google.com/patents/EP2838533A1?cl=en

In still other embodiments, the 15-PGDH inhibitor can be applied to skin of a subject to promote and/or stimulate pigmentation of the skin and/or hair growth and/or inhibit hair loss. The 15-PGDH inhibitor can also be administered to a subject to promote wound healing, regenerate tissue,

 

[hellouser]

Only one way to find out....

 

[dusty]

but 25mg is 750 dollars
http://www.apexbt.com/sw033291.html

 

[bboy5]

http://www.sciencealert.com/a-new-drug-has-been-found-that-fast-tracks-tissue-regeneration

The drug, which goes by the un-catchy name of ‘SW033291’, works by enabling a natural molecule in the body known as prostaglandin E2, or PGE2. Scientists have long known that PGE2 helps the proliferation of adult stem cells - which play a crucial role in healing by differentiating into new cell types as required within their tissue.
But in his earlier research, Markowitz had shown that there’s another gene product found in all humans known as 15-PGDH, which degrades and reduces the amount of PGE2. His team came up with the hypothesis that, if they could find a way to block 15-PGDH, they might be able to encourage tissue repair by keeping PGE2 levels high. So they set about finding a chemical that could do this – which is where SW033291 comes into the picture

 

[Mach]

I believe Hell mentioned that study a few months ago.

The dates on the patent are in 2012. Markowitz does research with colon cancer and most likely aware of the 30 year drug sulfasalazine. Putting 2 and 2 together a team THOUGHT of a good way to increase PGE2 in a gel. patent also mentions wounding. I haven't read the whole thing but I think it's more like "Yeah, I got an idea" some how the government got involved. I'd say it's more for the cancer patients to keep their hair during treatment than male pattern baldness.

 

[Mach]

There are other ways of keep pge2 levels high

thanks for the tip!

 

[hellouser]

thanks for the tip!

Look into sunburns.