Piroctone Olamine vs Nizoral

abovedagame

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So what is the consensun on Piroctone Olamine shampoo?

Does it really outperform nizoral and possibly act as an antiandrogen?

Where can I get my hands on some if I live in the US? The only one I could find was the ginger scalp care one by the Body Shop which doesn't list the concentration of PO.

Let me know about your experiences guys!

Thanks
 

Jaeger

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There is a study done on both that is somewhere on this site. Do a search and you just might find it. The amount of PO in the Ginger shampoo is less than 1% if i am not mistaken and i just started using it yesterday.
 

Maelstrom

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Jaeger said:
There is a study done on both that is somewhere on this site. Do a search and you just might find it. The amount of PO in the Ginger shampoo is less than 1% if i am not mistaken and i just started using it yesterday.

How's it going you guys that are using the Ginger shampoo with PO?
 

robert west

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Read the ingredients on the bottles in the dandruff shampoo section. There are several that contain piroctone olamine. I've read studies that it is a tad better than ketoconazole.
 

MrBastard

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I am interested in Piroctone Olamine aswell. I guess the study you have seen is this http://www.ncbi.nlm.nih.gov/pubmed/18498517

But my plan is to use a ABC cyclus. A - Keto shampoo, B - Piro O shampoo, C - An organic shampoo without SLS and other sh*t. Anyone else with experience if that helps at all or if it whould be better to just alter 2 shampoos?
 

robert west

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MrBastard, we must be coming across the same info! I too have read the bad stuff about SLS containing shampoos.
 

CCS

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abovedagame said:
So what is the consensun on Piroctone Olamine shampoo?

Does it really outperform nizoral and possibly act as an antiandrogen?

Where can I get my hands on some if I live in the US? The only one I could find was the ginger scalp care one by the Body Shop which doesn't list the concentration of PO.

Let me know about your experiences guys!

Thanks

I use both. You are not supposed to use one every day anyway.
 

CCS

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I read that piroctone olamine is pretty water soluble, at least if there is some alcohol in the water. Its antioxidant properties fight immune system oxidation of the follicle, and it is very stable at many pH's and temperatures.

I think ordering some and mixing it in with a minoxidil topical would be the way to go. Shampoos would be better, but they are hard to get.
 

Artas

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Is it safe to use a shampoo with Piroctone Olamine every other day?

Lately my hair has lost all its volume and I find it hard to style, I'm not sure why... but I am beginning to think it is linked with using the shampoo too much =/
 

CCS

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It just depends on your scalp. I did for a while. I read though that you are not supposed to shampoo every day, regardless of the shampoo.

I don't use any normal shampoos. I just use nizoral 3x per week, and I don't shampoo the other days. I want to get more piroctone olamine shampoo though. It is hard to find right now.
 

BetterLivinThruChemistry

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I really love piroctone olamine. I've had problems with scalp itching for years, and the Cien anti-dandruff shampoo with PO and salicylic acid is the best I have ever used. Furthermore, it is quite affordable (EUR 1.5) in Germany (where it scored first place in a test by Stiftung warentest), but you can find it most countries in which Lidl operate (though, alas, not in Italy, it seems). I use it everyday for problems with dandruff, itching and hairloss, and two-three days a week I mix it ~1:1 with a ketoconazol shampoo.
 

Flagermus

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I guess Piroctone Olamine is effective at fighting conditions like sebhoreic dermatitis, because of it's anti fungal effect. But as far as I understand PO doesn't have any anti inflammatory properties in the same way as Nizoral does, so it wouldn't be as helpful in reducing the inflammation that many think is one of the underlying reasons of male pattern baldness. Can someone confirm?
 

BetterLivinThruChemistry

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I don't know the answer to your question, but hopefully someone else will be able to give an answer. Anyways, I guess everyone knows about this study:

"Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations.

[Abstract]

Hair shedding and hair thinning have been reported to be affected by dandruff and seborrhoeic dermatitis. The present study was conducted in 150 men presenting with telogen effluvium related to androgenic alopecia associated with dandruff. They were randomly allocated to three groups receiving each one of the three shampoos in the market containing either 1% ketoconazole (KTZ), 1% piroctone olamine (PTO) or 1% zinc pyrithione (ZPT). Shampoos had to be used 2-3 times a week for 6 months. Hair shedding during shampoo was evaluated semiquantitatively. Hair density on the vertex was evaluated on photographs using a Dermaphot. Trichograms were used for determining the anagen hair percentage and the mean proximal hair shaft diameter using computerized image analysis. The sebum excretion rate (SER, mug cm(-2) h(-1)) was also measured using a Sebumeter. The three treatments cleared pruritus and dandruff rapidly. At end point, hair density was unchanged, although hair shedding was decreased (KTZ: -17.3%, PTO: -16.5%, ZPT: -10.1%) and the anagen hair percentage was increased (KTZ: 4.9%, PTO: 7.9%, ZPT: 6.8%). The effect on the mean hair shaft diameter was contrasted between the three groups of volunteers (KTZ: 5.4%, PTO: 7.7%, ZPT: -2.2%). In conclusion, telogen effluvium was controlled by KTZ, PTO and ZPT shampoos at 1% concentration. In addition, KTZ and PTO increased the mean hair shaft thickness while discretely decreasing the sebum output at the skin surface."

The shampo I mentioned in my previous post, also contains salicylic acid, which should reduce inflammation, right?
 

Flagermus

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Good point. Shampos like T/Gel and Cien combining PO and salicylic acid would probably also have the anti inflammatory effects of Nizoral.
 
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