Water
Very safe, especially in long run.
But I don't know if it will get the active ingredients in the best way. Grapeseed extract is not soluble in pure water.
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Propylene glycol
Inhalation:
No adverse health effects via inhalation.
Ingestion:
Relatively non-toxic. Ingestion of sizable amount (over 100ml) may cause some gastrointestinal upset and temporary central nervous system depression. Effects appear more severe in individuals with kidney problems.
Skin Contact:
Mild irritant and defatting agent, especially on prolonged contact.
Eye Contact:
May cause transitory stinging and tearing.
Chronic Exposure:
Lactic acidosis, stupor and seizures have been reported following chronic ingestion.
Aggravation of Pre-existing Conditions:
Kidney disorders.
PPG is a great solvent and good penetration enhanser
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Sorbitol
Toxicology
No known hazards.
Toxicity data
(The meaning of any abbreviations which appear in this section is given here.)
ORL-RAT LD50 16000 mg kg-1
SCU-RAT LD50 29600 mg kg-1
IVN-RAT LD50 7100 mg kg-1
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ethanol
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various oils and fatty acids
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octyl salicylate
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glycerol
Harmless.
Greesy, not a good penetration enhanser, but will dissolve anything. Soothing.
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pre-made vehicles like creams in the store. must see their ingredients
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OK, I have to knock out some homework, but i'll be back later.